Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).| Product Name | DDIT4 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DDIT4 antibody DDIT4_HUMAN antibody Dig2 antibody DNA damage inducible transcript 4 antibody DNA damage inducible transcript 4 protein antibody DNA damage-inducible transcript 4 protein antibody FLJ20500 antibody HIF 1 responsive protein RTP801 antibody HIF 1 responsive RTP801 antibody HIF-1 responsive protein RTP801 antibody Protein regulated in development and DNA damage response 1 antibody REDD-1 antibody REDD1 antibody RTP801 antibody |
| Product description | REDD-1, also designated DNA-damage-inducible transcript 4, dig2 or RTP801, is thought to function in the regulation of reactive oxygen species (ROS). REDD-1 expression has also been linked to apoptosis, Ab toxicity and the pathogenesis of ischemic diseases. As an HIF-1-responsive gene, REDD-1 exhibits strong hypoxia-dependent upregulation in ischemic cells of neuronal origin. In response to stress due to DNA damage and glucocorticoid treatment, REDD-1 is upregulated at the transcriptional level. REDD-1 negatively regulates the mammalian target of Rapamycin (mTOR), a serine/threonine kinase often referred to as FRAP. It is crucial in the coupling of extra- and intracellular cues to FRAP regulation. The absence of REDD-1 is associated with the development of retinopathy, a major cause of blindness. |
| Immunogen | Peptide. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHCFC |
| WB:1:500 ICC:1:50-1:100 IHC:1:50-1:200 FC:1:50-1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | DDIT4 antibody DDIT4_HUMAN antibody Dig2 antibody DNA damage inducible transcript 4 antibody DNA damage inducible transcript 4 protein antibody DNA damage-inducible transcript 4 protein antibody FLJ20500 antibody HIF 1 responsive protein RTP801 antibody HIF 1 responsive RTP801 antibody HIF-1 responsive protein RTP801 antibody Protein regulated in development and DNA damage response 1 antibody REDD-1 antibody REDD1 antibody RTP801 antibody |
|---|---|
| Molecular Weight(MW) | 25 kDa (Predicted band size） |
| Cellular Localization | Mitochondrion. Cytosol. |
Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Application
Fig8: Flow cytometric analysis of A549 cells with DDIT4 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).| Positive Control | Hela and K562 cell lysates, rat epididymis tissue, human tonsil tissue, human colon cancer tissue, human breast tissue, mouse colon tissue, A549. |
|---|---|
| Application Notes | WB:1:500 ICC:1:50-1:100 IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
