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NFkB p100 [JM82-03]

Catalog Number:OM628735
OM628735
Discount Price
OM628735-100ul
1~2 Week
100ul
OM628735-50ul
50ul
OM628735-20ul
20ul
1~2 Week
Product Profile
Product Name NFkB p100 [JM82-03]
Antibody Type Primary Antibodies
Antigen Alias CVID10 antibody DNA binding factor KBF2 antibody H2TF1 antibody Lymphocyte translocation chromosome 10 protein antibody LYT 10 antibody NF kB2 antibody NFKB p52/p100 subunit antibody Nuclear factor Kappa B subunit 2 antibody Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 (p49/p100) antibody Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 antibody Oncogene Lyt 10 antibody p100 antibody Transcription factor NFKB2 antibody
Product description NFKB2 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p100 and generation of p52 by a cotranslational processing. The proteasome-mediated process ensures the production of both p52 and p100 and preserves their independent function. p52 binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions. p52 and p100 are respectively the minor and major form; the processing of p100 being relatively poor. Isoform p49 is a subunit of the NF-kappa-B protein complex, which stimulates the HIV enhancer in synergy with p65.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBICC/IFIHCIP
WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names CVID10 antibody DNA binding factor KBF2 antibody H2TF1 antibody Lymphocyte translocation chromosome 10 protein antibody LYT 10 antibody NF kB2 antibody NFKB p52/p100 subunit antibody Nuclear factor Kappa B subunit 2 antibody Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 (p49/p100) antibody Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 antibody Oncogene Lyt 10 antibody p100 antibody Transcription factor NFKB2 antibody
Molecular Weight(MW) 100 kDa
Cellular Localization Cytoplasm. Nucleus.
Database Links
SwissProt ID Q00653 Q9WTK5
Application

Application

Fig6: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-NFkB p100 antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-NFkB p100 antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-NFkB p100 antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-NFkB p100 antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-NFkB p100 antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-NFkB p100 antibody. Counter stained with hematoxylin.
Positive Control Hela, MCF-7, A431, human tonsil tissue, human placenta tissue, human colon cancer tissue.
Application Notes WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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