Application
Fig1: Western blot analysis of ZBTB48 on mouse spleen tissue lysate using anti-ZBTB48 antibody at 1/1,000 dilution.Application
Fig2: ICC staining ZBTB48 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig3: ICC staining ZBTB48 in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-ZBTB48 antibody. Counter stained with hematoxylin.Application
Fig5: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-ZBTB48 antibody. Counter stained with hematoxylin.Application
Fig6: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-ZBTB48 antibody. Counter stained with hematoxylin.Application
Fig7: Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-ZBTB48 antibody. Counter stained with hematoxylin.Application
Fig8: Flow cytometric analysis of Hela cells with ZBTB48 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.| Product Name | ZBTB48 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 0610011D15Rik antibody AI327031 antibody GLI Kruppel family member HKR3 antibody HKR3 antibody Krueppel related zinc finger protein 3 antibody Krueppel-related zinc finger protein 3 antibody OTTMUSP00000031803 antibody pp9964 antibody Protein HKR3 antibody RP23-445E20.3 antibody ZBT48_HUMAN antibody ZBTB 48 antibody Zbtb48 antibody Zinc finger and BTB domain containing 48 antibody Zinc finger and BTB domain containing protein 48 antibody Zinc finger and BTB domain-containing protein 48 antibody Zinc finger protein 855 antibody ZNF855 antibody |
| Product description | Telomere-binding protein that acts as a regulator of telomere length. Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat. Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres. Also acts as a transcription regulator that binds to promoter regions. Regulates expression of a small subset of genes, including MTFP1. Regulates expression the J and/or S elements in MHC II promoter. Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A. |
| Immunogen | Peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHCFC |
| WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | 0610011D15Rik antibody AI327031 antibody GLI Kruppel family member HKR3 antibody HKR3 antibody Krueppel related zinc finger protein 3 antibody Krueppel-related zinc finger protein 3 antibody OTTMUSP00000031803 antibody pp9964 antibody Protein HKR3 antibody RP23-445E20.3 antibody ZBT48_HUMAN antibody ZBTB 48 antibody Zbtb48 antibody Zinc finger and BTB domain containing 48 antibody Zinc finger and BTB domain containing protein 48 antibody Zinc finger and BTB domain-containing protein 48 antibody Zinc finger protein 855 antibody ZNF855 antibody |
|---|---|
| Molecular Weight(MW) | 77 kDa |
| Cellular Localization | Nucleus. |
Application
Fig1: Western blot analysis of ZBTB48 on mouse spleen tissue lysate using anti-ZBTB48 antibody at 1/1,000 dilution.
Application
Fig2: ICC staining ZBTB48 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: ICC staining ZBTB48 in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-ZBTB48 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-ZBTB48 antibody. Counter stained with hematoxylin.
Application
Fig6: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-ZBTB48 antibody. Counter stained with hematoxylin.
Application
Fig7: Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-ZBTB48 antibody. Counter stained with hematoxylin.
Application
Fig8: Flow cytometric analysis of Hela cells with ZBTB48 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.| Positive Control | Mouse spleen tissue lysate, HepG2, PC-3M, SH-SY5Y, human liver cancer tissue, human kidney tissue, mouse kidney tissue, rat kidney tissue. |
|---|---|
| Application Notes | WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
