Application
Fig1: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PLGF antibody. Counter stained with hematoxylin.Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-PLGF antibody. Counter stained with hematoxylin.Application
Fig3: Flow cytometric analysis of SH-SY5Y cells with PLGF antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.| Product Name | PLGF |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | D12S1900 antibody Pgf antibody PGFL antibody PIGF antibody Placenta growth factor antibody Placental growth factor antibody Placental growth factor, vascular endothelial growth factor related protein antibody PlGF 2 antibody PlGF antibody PLGF_HUMAN antibody PlGF2 antibody SHGC 10760 antibody |
| Product description | The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factor (FGF), platelet derived growth factor (PDGF), vascular endothelial growth factor (VEGF) and placenta growth factor (PlGF). Like VEGF, several PlGF variants have been shown to arise from alternative mRNA splicings. Evidence has suggested VEGF to be an obligatory component in PlGF signaling. While VEGF homodimers and VEGF/PlGF heterodimers function as potent mediators of mitogenic and chemotactic responses in endothelial cells, PlGF homodimers are effectual only at extremely high concentrations. Indeed, many of the physiological effects attributed to VEGF may actually be a result of VEGF/PlGF. VEGF and PlGF share a common receptor, Flt-1, and may also activate Flk-1/KDR. |
| Immunogen | Recombinant protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCFC |
| IHC:1:50-1:200 FC:1:50-1:100 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | D12S1900 antibody
Pgf antibody
PGFL antibody
PIGF antibody
Placenta growth factor antibody
Placental growth factor antibody
Placental growth factor vascular endothelial growth factor related protein antibody PlGF 2 antibody PlGF antibody PLGF_HUMAN antibody PlGF2 antibody SHGC 10760 antibody |
|---|---|
| Molecular Weight(MW) | 24 kDa |
| Cellular Localization | Secreted. |
Application
Fig1: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PLGF antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-PLGF antibody. Counter stained with hematoxylin.
Application
Fig3: Flow cytometric analysis of SH-SY5Y cells with PLGF antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.| Positive Control | Human kidney tissue, mouse testis tissue, SH-SY5Y. |
|---|---|
| Application Notes | IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
