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TXNIP [JM60-35]
Catalog Number:OM628795
OM628795
Discount Price
OM628795-100ul
1~2 Week
100ul
OM628795-50ul
50ul
OM628795-20ul
20ul
1~2 Week
Product Profile
Product Name TXNIP [JM60-35]
Antibody Type Primary Antibodies
Antigen Alias EST01027 antibody HHCPA78 antibody THIF antibody Thioredoxin binding protein 2 antibody Thioredoxin interacting protein antibody Thioredoxin-binding protein 2 antibody Thioredoxin-interacting protein antibody TXNIP antibody TXNIP_HUMAN antibody Upregulated by 1,25 dihydroxyvitamin D 3 antibody VDUP1 antibody Vitamin D3 up-regulated protein 1 antibody
Product description May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBICC/IFIHCFC
WB:1:500~1:2000
ICC/IF:1:200~1:500
IHC:1:50~1:200
FC:1:200~1:500
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names EST01027 antibody HHCPA78 antibody THIF antibody Thioredoxin binding protein 2 antibody Thioredoxin interacting protein antibody Thioredoxin-binding protein 2 antibody Thioredoxin-interacting protein antibody TXNIP antibody TXNIP_HUMAN antibody Upregulated by 1
25 dihydroxyvitamin D 3 antibody VDUP1 antibody Vitamin D3 up-regulated protein 1 antibody
Molecular Weight(MW) 44 kDa
Cellular Localization Cytoplasm.
Database Links
Application

Application

Fig9: Flow cytometric analysis of Hela cells with TXNIP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig9: Flow cytometric analysis of Hela cells with TXNIP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig9: Flow cytometric analysis of Hela cells with TXNIP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig9: Flow cytometric analysis of Hela cells with TXNIP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig9: Flow cytometric analysis of Hela cells with TXNIP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig9: Flow cytometric analysis of Hela cells with TXNIP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig9: Flow cytometric analysis of Hela cells with TXNIP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig9: Flow cytometric analysis of Hela cells with TXNIP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig9: Flow cytometric analysis of Hela cells with TXNIP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Positive Control PC-12 cell lysate, human skeletal muscle tissue lysate, NIH-3T3, Hela, SH-SY5Y, human kidney tissue, human stomach cancer tissue, mouse kidney tissue, mouse stomach tissue.
Application Notes WB:1:500~1:2000
ICC/IF:1:200~1:500
IHC:1:50~1:200
FC:1:200~1:500
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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