Application
Fig1: Western blot analysis of SAE2/UBA2 on A549 (1) and PC-12 (2) cell lysate using anti-SAE2/UBA2 antibody at 1/500 dilution.| Product Name | SAE2/ UBA2 [JM66-53] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Anthracycline associated resistance ARX antibody Anthracycline-associated resistance ARX antibody ARX antibody FLJ13058 antibody HRIHFB2115 antibody SAE 2 antibody SAE2 antibody SAE2_HUMAN antibody SUMO 1 activating enzyme subunit 2 antibody SUMO activating enzyme subunit 2 antibody SUMO-activating enzyme subunit 2 antibody UBA2 antibody UBA2 ubiquitin activating enzyme E1 homolog antibody Ubiquitin like 1 activating enzyme E1B antibody Ubiquitin like modifier activating enzyme 2 antibody Ubiquitin-like 1-activating enzyme E1B antibody UBLE1B antibody |
| Product description | The small ubiquitin-related modifier protein SUMO-1 belongs to the ubiquitin-like protein family, which are synthesized as precursor proteins that undergo processing before conjugation to target proteins. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processes, including nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO-1 utilizes homologues of the E1 and E2 enzymes for conjugation to proteins, which include IkBα, MDM2, p53, PML, and RanGap1. AOS1 is homologous to the N-terminal half of E1 and UBA2 is homologous to the C-terminal half of E1. These proteins form a heterodimer that activates SUMO-1. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIP |
| WB:1:500 IP:1:10-1:50 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | Anthracycline associated resistance ARX antibody Anthracycline-associated resistance ARX antibody ARX antibody FLJ13058 antibody HRIHFB2115 antibody SAE 2 antibody SAE2 antibody SAE2_HUMAN antibody SUMO 1 activating enzyme subunit 2 antibody SUMO activating enzyme subunit 2 antibody SUMO-activating enzyme subunit 2 antibody UBA2 antibody UBA2 ubiquitin activating enzyme E1 homolog antibody Ubiquitin like 1 activating enzyme E1B antibody Ubiquitin like modifier activating enzyme 2 antibody Ubiquitin-like 1-activating enzyme E1B antibody UBLE1B antibody |
|---|---|
| Molecular Weight(MW) | 71 kDa |
| Cellular Localization | Nucleus. |
Application
Fig1: Western blot analysis of SAE2/UBA2 on A549 (1) and PC-12 (2) cell lysate using anti-SAE2/UBA2 antibody at 1/500 dilution.| Positive Control | A549, Hela, PC-12. |
|---|---|
| Application Notes | WB:1:500 IP:1:10-1:50 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
