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ALIX [JM85-31]

Catalog Number:OM628798
OM628798
Discount Price
OM628798-100ul
1~2 Week
100ul
OM628798-50ul
50ul
OM628798-20ul
20ul
1~2 Week
Product Profile
Product Name ALIX [JM85-31]
Antibody Type Primary Antibodies
Antigen Alias AIP1 antibody ALG 2 interacting protein 1 antibody ALG-2-interacting protein 1 antibody ALG2 interacting protein X antibody Alix antibody Apoptosis linked gene 2 interacting protein X antibody Dopamine receptor interacting protein 4 antibody DRIP4 antibody Hp95 antibody KIAA1375 antibody MGC17003 antibody PDC6I_HUMAN antibody PDCD6 interacting protein antibody PDCD6-interacting protein antibody PDCD6IP antibody Programmed cell death 6 interacting protein antibody Programmed cell death 6-interacting protein antibody
Product description ALG-2-interacting protein (Alix), also designated programmed cell death 6-interacting protein (PDCD6-interacting protein), is a cytoplasmic protein. Alix interacts with apoptosis-associated proteins (ALG-2 and PDCD6) and with the endocytosis-regulator CIN85. Additionally, Alix interacts with the endosomal sorting complexes required for transport (ESCRT) proteins (Tsg101 and CHMP4) and can associate with HIV-1. The endophilins (SH3P4, SH3P8 and SH3P13), enzymes that change curvature of the membrane that are required for early and late steps of coated vesicle formation, also bind to Alix. Alix is involved in the concentration and sorting of cargo proteins of the multivesicular body for incorporation into vesicles.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBIHCFC
WB:1:500~1:2000
IHC:1:50~1:200
FC:1:200~1:500
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names AIP1 antibody ALG 2 interacting protein 1 antibody ALG-2-interacting protein 1 antibody ALG2 interacting protein X antibody Alix antibody Apoptosis linked gene 2 interacting protein X antibody Dopamine receptor interacting protein 4 antibody DRIP4 antibody Hp95 antibody KIAA1375 antibody MGC17003 antibody PDC6I_HUMAN antibody PDCD6 interacting protein antibody PDCD6-interacting protein antibody PDCD6IP antibody Programmed cell death 6 interacting protein antibody Programmed cell death 6-interacting protein antibody
Molecular Weight(MW) 96 kDa
Cellular Localization Cytoplasm. Cytoskeleton.
Database Links
Application

Application

Fig5: Flow cytometric analysis of Jurkat cells with ALIX antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig5: Flow cytometric analysis of Jurkat cells with ALIX antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig5: Flow cytometric analysis of Jurkat cells with ALIX antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig5: Flow cytometric analysis of Jurkat cells with ALIX antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Application

Fig5: Flow cytometric analysis of Jurkat cells with ALIX antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Positive Control Hela, PC-12, NIH-3T3, rat stomach tissue, human colon cancer tissue, human prostate tissue, Jurkat.
Application Notes WB:1:500~1:2000
IHC:1:50~1:200
FC:1:200~1:500
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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