Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Epac1 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Epac1 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Epac1 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Epac1 antibody. Counter stained with hematoxylin.| Product Name | Epac1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | bcm910 antibody CAMP GEFI antibody cAMP regulated guanine nucleotide exchange factor I antibody CAMPGEFI antibody CGEF 1 antibody CGEF1 antibody EPA1 antibody Epac 1 antibody EPAC antibody EPAC1 antibody Exchange factor directly activated by cAMP 1 antibody Exchange protein directly activated by cAMP 1 antibody MGC21410 antibody RAP guanine nucleotide exchange factor antibody Rap guanine nucleotide exchange factor (GEF) 3 antibody RAP guanine nucleotide exchange factor 3 antibody Rap1 guanine nucleotide exchange factor directly activated by cAMP antibody RAPGEF3 antibody |
| Product description | 3',5' cyclic adenosine monophosphate (cAMP)-regulated guanine nucleotide exchange factors Epac (Epac1, cAMP-GEFI) and Epac2 (cAMP-GEFII) activate the Ras family GTPases Rap 1 and Rap 2 by promoting GTP binding in a cAMP-dependent manner. Eukaryotic cAMP is a second messenger that induces physiological responses such as gene expression, growth, differentiation, secretion and neurotransmission. The human Epac gene maps to chromosome 12q13.11 with transcript being abundant in the kidney and heart. In situ hybridization indicates expression of Epac in adult rat brain and selective expression in neonatal brain, including septum and thalamus. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCIPICC/IF |
| WB:1:500-1:1,000 IHC:1:50-1:200 IP:1:10-1:50 ICC/IF:1:10-1:50 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | bcm910 antibody CAMP GEFI antibody cAMP regulated guanine nucleotide exchange factor I antibody CAMPGEFI antibody CGEF 1 antibody CGEF1 antibody EPA1 antibody Epac 1 antibody EPAC antibody EPAC1 antibody Exchange factor directly activated by cAMP 1 antibody Exchange protein directly activated by cAMP 1 antibody MGC21410 antibody RAP guanine nucleotide exchange factor antibody Rap guanine nucleotide exchange factor (GEF) 3 antibody RAP guanine nucleotide exchange factor 3 antibody Rap1 guanine nucleotide exchange factor directly activated by cAMP antibody RAPGEF3 antibody |
|---|---|
| Cellular Localization | Endomembrane system. |
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Epac1 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Epac1 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Epac1 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Epac1 antibody. Counter stained with hematoxylin.| Positive Control | Mouse kidney tissue lysate, human prostate tissue, human stomach cancer tissue, mouse kidney tissue. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IHC:1:50-1:200 IP:1:10-1:50 ICC/IF:1:10-1:50 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
