Application
Fig1: Western blot analysis of FTO on different lysates using anti-FTO antibody at 1/1,000 dilution. Positive control: Lane 1: Human fetal brain tissue Lane 2: HepG2 Lane 3: 293Application
Fig2: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-FTO antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-FTO antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-FTO antibody. Counter stained with hematoxylin.| Product Name | FTO |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AlkB homolog 9 antibody ALKBH9 antibody Alpha-ketoglutarate-dependent dioxygenase FTO antibody AW743446 antibody Fat mass and obesity-associated protein antibody FATSO, MOUSE, HOMOLOG OF antibody Fto antibody FTO_HUMAN antibody GDFD antibody KIAA1752 antibody mKIAA1752 antibody Protein fatso antibody |
| Product description | FTO, also known as Fatso or KIAA1752, is a 505 amino acid protein that has an N-terminal nuclear localization signal. Expressed in a variety of tissues, with highest levels present in brain and pancreatic tissue, Fatso exists as four alternatively spliced isoforms, one of which is associated with a predisposition to childhood and adult obesity. Due to its involvement in the development of obesity, Fatso is associated with an increased BMI and may be involved in the pathogenesis of type 2 diabetes. The gene encoding Fatso maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2,000 IHC:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | AlkB homolog 9 antibody
ALKBH9 antibody
Alpha-ketoglutarate-dependent dioxygenase FTO antibody
AW743446 antibody
Fat mass and obesity-associated protein antibody
FATSO MOUSE HOMOLOG OF antibody Fto antibody FTO_HUMAN antibody GDFD antibody KIAA1752 antibody mKIAA1752 antibody Protein fatso antibody |
|---|---|
| Cellular Localization | Nucleus. |
| SwissProt ID | Q9C0B1 |
|---|
Application
Fig1: Western blot analysis of FTO on different lysates using anti-FTO antibody at 1/1,000 dilution. Positive control: Lane 1: Human fetal brain tissue Lane 2: HepG2 Lane 3: 293
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-FTO antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-FTO antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-FTO antibody. Counter stained with hematoxylin.| Positive Control | Human fetal brain tissue lysate, HepG2, 293, human placenta tissue, human pancreas tissue, human uterus tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
