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Ki67
Catalog Number:OM628828
OM628828
Discount Price
OM628828-100ul
1~2 Week
100ul
OM628828-50ul
50ul
OM628828-20ul
20ul
1~2 Week
Product Profile
Product Name Ki67
Antibody Type Primary Antibodies
Antigen Alias Antigen identified by monoclonal antibody Ki 67 antibody Antigen identified by monoclonal antibody Ki-67 antibody Antigen KI-67 antibody Antigen KI67 antibody Antigen Ki67 antibody KI67_HUMAN antibody KIA antibody Marker of proliferation Ki-67 antibody MIB 1 antibody MIB antibody MKI67 antibody PPP1R105 antibody Proliferation marker protein Ki-67 antibody Proliferation related Ki 67 antigen antibody Protein phosphatase 1 regulatory subunit 105 antibody RP11-380J17.2 antibody
Product description Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization. It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable).
Immunogen Peptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:500
IHC:1:50-1:200
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names Antigen identified by monoclonal antibody Ki 67 antibody Antigen identified by monoclonal antibody Ki-67 antibody Antigen KI-67 antibody Antigen KI67 antibody Antigen Ki67 antibody KI67_HUMAN antibody KIA antibody Marker of proliferation Ki-67 antibody MIB 1 antibody MIB antibody MKI67 antibody PPP1R105 antibody Proliferation marker protein Ki-67 antibody Proliferation related Ki 67 antigen antibody Protein phosphatase 1 regulatory subunit 105 antibody RP11-380J17.2 antibody
Molecular Weight(MW) 359 kDa
Cellular Localization Nucleus.
Database Links
SwissProt ID P46013
Application

Application

Fig1: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Ki67 antibody. Counter stained with hematoxylin.

Application

Fig2: Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Ki67 antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-Ki67 antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue using anti-Ki67 antibody. Counter stained with hematoxylin.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue using anti-Ki67 antibody. Counter stained with hematoxylin. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6) for 20 mins.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded rat large intestine tissue using anti-Ki67 antibody. Counter stained with hematoxylin. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6) for 20 mins.
Positive Control Human tonsil tissue, human lung cancer tissue, human colon cancer tissue, human stomach cancer tissue.
Application Notes WB:1:500
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
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