Application
Fig1: Western blot analysis of IL1 alpha on human lymph node lysates using anti-IL1 alpha antibody at 1/500 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-IL1 alpha antibody. Counter stained with hematoxylin.Application
Fig3: Flow cytometric analysis of PC-3M cells with IL1 alpha antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.| Product Name | IL1 alpha |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BAF antibody FAF antibody Hematopoietin 1 antibody Hematopoietin-1 antibody IL 1 alpha antibody IL 1A antibody IL-1 alpha antibody Il-1a antibody IL1 ALPHA antibody IL1 antibody IL1A antibody IL1A_HUMAN antibody IL1F1 antibody Interleukin 1 alpha antibody Interleukin-1 alpha antibody Interleukin1 alpha antibody LAF antibody LEM antibody Preinterleukin 1 alpha antibody Pro interleukin 1 alpha antibody |
| Product description | Two forms of interleukin-1, designated IL-1α and IL-1β, have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1α and IL-1β bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer (NK) cells. In T cells, IL-1 stimulates the production of IL-2 and selectively inhibits IL-4 expression. IL-1 induces B cell proliferation and maturation, and immunoglobulin synthesis. NK cells require IL-1β for production of the anti- pathogen IFN-γ. IL-1 has also been implicated in several pathological conditions including rheumatoid arthritis, inflammatory bowel disease and atherosclerosis. |
| Immunogen | Recombinant protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCFCWB |
| IHC:1:400-1:800 FC:1:50-1:100 WB:1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | BAF antibody FAF antibody Hematopoietin 1 antibody Hematopoietin-1 antibody IL 1 alpha antibody IL 1A antibody IL-1 alpha antibody Il-1a antibody IL1 ALPHA antibody IL1 antibody IL1A antibody IL1A_HUMAN antibody IL1F1 antibody Interleukin 1 alpha antibody Interleukin-1 alpha antibody Interleukin1 alpha antibody LAF antibody LEM antibody Preinterleukin 1 alpha antibody Pro interleukin 1 alpha antibody |
|---|---|
| Molecular Weight(MW) | 31 kDa |
| Cellular Localization | Secreted. |
Application
Fig1: Western blot analysis of IL1 alpha on human lymph node lysates using anti-IL1 alpha antibody at 1/500 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-IL1 alpha antibody. Counter stained with hematoxylin.
Application
Fig3: Flow cytometric analysis of PC-3M cells with IL1 alpha antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.| Positive Control | Human lymph node lysates, Human colon cancer tissue, PC-3M. |
|---|---|
| Application Notes | IHC:1:400-1:800 FC:1:50-1:100 WB:1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
