Application
Fig1: IF analysis of paraffin-embedded human pancreas tissue using anti-PDX1 antibody (green）. The nuclear counter stain is DAPI (blue).Application
Fig2: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-PDX1 antibody. Counter stained with hematoxylin.| Product Name | PDX1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Glucose sensitive factor antibody Glucose-sensitive factor antibody GSF antibody IDX 1 antibody IDX-1 antibody IDX1 antibody Insulin promoter factor 1 antibody Insulin promoter factor 1 homeodomain transcription factor antibody Insulin upstream factor 1 antibody IPF 1 antibody IPF-1 antibody IPF1 antibody Islet/duodenum homeobox 1 antibody Islet/duodenum homeobox-1 antibody IUF 1 antibody IUF-1 antibody IUF1 antibody MODY4 antibody Pancreas/duodenum homeobox 1 antibody Pancreas/duodenum homeobox protein 1 antibody pancreatic and duodenal homeobox P antibody PDX 1 antibody PDX-1 antibody PDX1 antibody PDX1_HUMAN antibody Somatostatin transactivating factor 1 antibody Somatostatin-transactivating factor 1 antibody STF 1 antibody STF-1 antibody STF1 antibody |
| Product description | Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCICC/IF |
| IHC:1:50-1:200 ICC/IF:1:50-1:200 WB:1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Glucose sensitive factor antibody
Glucose-sensitive factor antibody GSF antibody IDX 1 antibody IDX-1 antibody IDX1 antibody Insulin promoter factor 1 antibody Insulin promoter factor 1 homeodomain transcription factor antibody Insulin upstream factor 1 antibody IPF 1 antibody IPF-1 antibody IPF1 antibody Islet/duodenum homeobox 1 antibody Islet/duodenum homeobox-1 antibody IUF 1 antibody IUF-1 antibody IUF1 antibody MODY4 antibody Pancreas/duodenum homeobox 1 antibody Pancreas/duodenum homeobox protein 1 antibody pancreatic and duodenal homeobox P antibody PDX 1 antibody PDX-1 antibody PDX1 antibody PDX1_HUMAN antibody Somatostatin transactivating factor 1 antibody Somatostatin-transactivating factor 1 antibody STF 1 antibody STF-1 antibody STF1 antibody |
|---|---|
| Cellular Localization | Cytosol, Nucleus. |
| SwissProt ID | P52945 |
|---|
Application
Fig1: IF analysis of paraffin-embedded human pancreas tissue using anti-PDX1 antibody (green）. The nuclear counter stain is DAPI (blue).
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-PDX1 antibody. Counter stained with hematoxylin.| Positive Control | Human pancreas tissue. |
|---|---|
| Application Notes | IHC:1:50-1:200 ICC/IF:1:50-1:200 WB:1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
