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APOC3

Catalog Number:OM628856
OM628856
Discount Price
OM628856-100ul
1~2 Week
100ul
OM628856-50ul
50ul
OM628856-20ul
20ul
1~2 Week
Product Profile
Product Name APOC3
Antibody Type Primary Antibodies
Antigen Alias APOC3 antibody APO C3 antibody Apo CIII antibody Apo-CIII antibody APOC 3 antibody ApoC III antibody ApoC-III antibody APOC3 antibody APOC3_HUMAN antibody ApoCIII antibody Apolipoprotein C III antibody Apolipoprotein C-III antibody Apolipoprotein C3 antibody ApolipoproteinCIII antibody MGC150353 antibody
Product description Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners.
Immunogen Recombinant protein with Human APOC3 aa 1-100.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:500-1:2000
IHC:1:50-1:200
FC:1:50-1:100
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names APOC3 antibody APO C3 antibody Apo CIII antibody Apo-CIII antibody APOC 3 antibody ApoC III antibody ApoC-III antibody APOC3 antibody APOC3_HUMAN antibody ApoCIII antibody Apolipoprotein C III antibody Apolipoprotein C-III antibody Apolipoprotein C3 antibody ApolipoproteinCIII antibody MGC150353 antibody
Molecular Weight(MW) 11 kDa
Cellular Localization Secreted.
Database Links
SwissProt ID P02656
Application

Application

Fig1: Western blot analysis of APOC3 on human liver tissue lysate using anti-APOC3 antibody at 1/500 dilution.

Application

Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-APOC3 antibody. Counter stained with hematoxylin.

Application

Fig3: Flow cytometric analysis of HepG2 cells with APOC3 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Positive Control Human liver tissue, HepG2.
Application Notes WB:1:500-1:2000
IHC:1:50-1:200
FC:1:50-1:100
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
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