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TROP2

Catalog Number:OM628883
OM628883
Discount Price
OM628883-100ul
1~2 Week
100ul
OM628883-50ul
50ul
OM628883-20ul
20ul
1~2 Week
Product Profile
Product Name TROP2
Antibody Type Primary Antibodies
Antigen Alias Cell surface glycoprotein Trop 2 antibody Cell surface glycoprotein Trop-2 antibody Cell surface glycoprotein Trop2 antibody Epithelial glycoprotein 1 antibody GA733 1 antibody GA7331 antibody M1S 1 antibody M1S1 antibody Membrane component chromosome 1 surface marker 1 antibody Pancreatic carcinoma marker protein GA733 1 antibody Pancreatic carcinoma marker protein GA733-1 antibody Pancreatic carcinoma marker protein GA7331 antibody TACD 2 antibody TACD2_HUMAN antibody TACSTD 2 antibody Tacstd2 antibody Trop 2 antibody Trop2 antibody Tumor associated calcium signal transducer 2 precursor antibody Tumor-associated calcium signal transducer 2 antibody
Product description TROP-2, also known as tumor-associated calcium signal transducer 2 (TACSTD2), pancreatic carcinoma marker protein GA733-1, membrane component chromosome 1, surface marker 1 (M1S1) or epithelial glycoprotein-1 (EGP-1), is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thryoglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. TROP-2 plays a role in tranducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multistratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells. Mutations in the gene encoding TROP-2 can result in gelatinous drop-like corneal dystrophy (GDLD) also referred to as lattice corneal dystrophy type III, an autosomal recessive disorder that causes severe visual impairment.
Immunogen Recombinant protein.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBICCIHC
WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names Cell surface glycoprotein Trop 2 antibody Cell surface glycoprotein Trop-2 antibody Cell surface glycoprotein Trop2 antibody Epithelial glycoprotein 1 antibody GA733 1 antibody GA7331 antibody M1S 1 antibody M1S1 antibody Membrane component chromosome 1 surface marker 1 antibody Pancreatic carcinoma marker protein GA733 1 antibody Pancreatic carcinoma marker protein GA733-1 antibody Pancreatic carcinoma marker protein GA7331 antibody TACD 2 antibody TACD2_HUMAN antibody TACSTD 2 antibody Tacstd2 antibody Trop 2 antibody Trop2 antibody Tumor associated calcium signal transducer 2 precursor antibody Tumor-associated calcium signal transducer 2 antibody
Molecular Weight(MW) 35 kDa
Cellular Localization Membrane.
Database Links
SwissProt ID P09758
Application

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human esophagus tissue using anti-TROP2 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human esophagus tissue using anti-TROP2 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human esophagus tissue using anti-TROP2 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human esophagus tissue using anti-TROP2 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human esophagus tissue using anti-TROP2 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human esophagus tissue using anti-TROP2 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human esophagus tissue using anti-TROP2 antibody. Counter stained with hematoxylin.
Positive Control A431, human lung cancer tissue, human liver cancer tissue, human colon cancer tissue, human breasr cancer tissue, human esophagus tissue.
Application Notes WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
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