Application
Fig1: Western blot analysis of HSD11B1 on mouse liver tissue lysate using anti-HSD11B1 antibody at 1/500 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-HSD11B1 antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-HSD11B1 antibody. Counter stained with hematoxylin.| Product Name | HSD11B1 [JU18-39] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 11 beta HSD 1 antibody 11 beta HSD1 antibody 11 beta hydroxysteroid dehydrogenase 1 antibody 11 DH antibody 11-beta hydroxysteroid dehydrogenase, type 1 antibody 11-beta-HSD1 antibody 11-beta-hydroxysteroid dehydrogenase 1 antibody 11-DH antibody 11DH antibody Corticosteroid 11 beta dehydrogenase isozyme 1 antibody Corticosteroid 11-beta-dehydrogenase isozyme 1 antibody CORTRD2 antibody DHI1_HUMAN antibody HDL antibody HSD 11 antibody HSD11 antibody HSD11B antibody HSD11B1 antibody HSD11L antibody Hydroxysteroid (11 beta) dehydrogenase antibody Hydroxysteroid (11 beta) dehydrogenase 1 antibody MGC13539 antibody SDR26C1 antibody short chain dehydrogenase/reductase family 26C, member 1 antibody |
| Product description | HSD11B1(Corticosteroid 11-beta-dehydrogenase isozyme 1) is also named as HSD11, HSD11L,11-DH and 11-beta-HSD1.It is a microsomal enzyme, which acts mainly as a NADP(H)- dependent reductase converting inactive cortisone (E) to active cortisol (F), thus regulating intracellular F access to glucocorticoid receptor. This enzyme is widely expressed not only in liver and adipose tissue, but also in adrenal, ovary and decidua.Western blot analysis in human liver, using a specific11-beta-HSD1 antibody, showed two bands at approximately 34 and 68 kDa confrming the dimeric nature of 11-beta-HSD1 in liver and In omental adipose tissue, an additional band of 50 kDa was strongly expressed. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2,000 IHC:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | 11 beta HSD 1 antibody
11 beta HSD1 antibody
11 beta hydroxysteroid dehydrogenase 1 antibody
11 DH antibody
11-beta hydroxysteroid dehydrogenase type 1 antibody 11-beta-HSD1 antibody 11-beta-hydroxysteroid dehydrogenase 1 antibody 11-DH antibody 11DH antibody Corticosteroid 11 beta dehydrogenase isozyme 1 antibody Corticosteroid 11-beta-dehydrogenase isozyme 1 antibody CORTRD2 antibody DHI1_HUMAN antibody HDL antibody HSD 11 antibody HSD11 antibody HSD11B antibody HSD11B1 antibody HSD11L antibody Hydroxysteroid (11 beta) dehydrogenase antibody Hydroxysteroid (11 beta) dehydrogenase 1 antibody MGC13539 antibody SDR26C1 antibody short chain dehydrogenase/reductase family 26C member 1 antibody |
|---|---|
| Molecular Weight(MW) | 32 kDa |
| Cellular Localization | Endoplasmic reticulum, Membrane. |
Application
Fig1: Western blot analysis of HSD11B1 on mouse liver tissue lysate using anti-HSD11B1 antibody at 1/500 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-HSD11B1 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-HSD11B1 antibody. Counter stained with hematoxylin.| Positive Control | Mouse liver tissue lysate, human liver tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
