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Dynamin 1

Catalog Number:OM628912
OM628912
Discount Price
OM628912-100ul
1~2 Week
100ul
OM628912-50ul
50ul
OM628912-20ul
20ul
1~2 Week
Product Profile
Product Name Dynamin 1
Antibody Type Primary Antibodies
Antigen Alias B dynamin antibody D100 antibody DNM 1 antibody DNM antibody DNM1 antibody DYN1_HUMAN antibody Dynamin antibody Dynamin-1 antibody Dynamin1 antibody
Product description Members of the Dynamin family, including Dynamin I and Dynamin II, are GTPase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression found in testis. Both dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the dynamins and effectors of their GTPase activity). The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to clathrin coated pits by SH3 domain interaction with amphiphysin, a protein highly expressed in brain.
Immunogen Recombinant protein within human Dynamin 1 aa 575-750.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:500-1:1,000
IHC:1:50-1:200
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names B dynamin antibody D100 antibody DNM 1 antibody DNM antibody DNM1 antibody DYN1_HUMAN antibody Dynamin antibody Dynamin-1 antibody Dynamin1 antibody
Molecular Weight(MW) 97 kDa
Cellular Localization Cytoplasm. Cytoskeleton.
Database Links
Application

Application

Fig1: Western blot analysis of Dynamin 1 on mouse brain tissue lysate using anti-Dynamin 1 antibody at 1/500 dilution.

Application

Fig2: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Dynamin 1 antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Dynamin 1 antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue using anti-Dynamin 1 antibody. Counter stained with hematoxylin.
Positive Control Mouse brain tissue, rat brain tissue, mouse cerebellum tissue.
Application Notes WB:1:500-1:1,000
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
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