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HDAC9 [JU30-44]

Catalog Number:OM628926
OM628926
Discount Price
OM628926-100ul
1~2 Week
100ul
OM628926-50ul
50ul
OM628926-20ul
20ul
1~2 Week
Product Profile
Product Name HDAC9 [JU30-44]
Antibody Type Primary Antibodies
Antigen Alias HD 7 antibody HD 7B antibody HD 9 antibody HD7 antibody HD7B antibody HD9 antibody HDAC 7 antibody HDAC 7B antibody HDAC 9 antibody HDAC 9B antibody HDAC 9FL antibody HDAC antibody HDAC7 antibody HDAC7B antibody HDAC9 antibody HDAC9_HUMAN antibody HDAC9B antibody HDAC9FL antibody HDRP antibody Histone deacetylase 4/5 related protein antibody Histone deacetylase 7 antibody Histone deacetylase 7B antibody Histone deacetylase 9 antibody Histone deacetylase 9A antibody Histone deacetylase related protein antibody Histone deacetylase-related protein antibody KIAA0744 antibody MEF2 interacting transcription repressor MITR antibody MEF2 interacting transcription repressor protein antibody MEF2-interacting transcription repressor MITR antibody MITR antibody
Product description In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is a critical component of transcriptional regulation and the acetylation of nucleosomal histones is a major source of this remodeling. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Several mammalian proteins function as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250. Conversely, the deacetylation of histones is associated with transcriptional silencing. The histone deacetylases (HDAC) include HDAC1-9. HDAC9 and HDAC9a are two alternatively spliced isoforms of HDAC9. HDAC9a is 132 amino acids shorter than HDAC9, but both isoforms contain the HDAC catalytic domain, remain capable of deacetylase activity and repress myoctye enhancer-binding factor 2-mediated transcription.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBICC/IFIHCIP
WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
IP:1:10-1:50
Species Reactivity HumanRat
Concentration 1mg/ml
Target Information
Alternative Names HD 7 antibody HD 7B antibody HD 9 antibody HD7 antibody HD7B antibody HD9 antibody HDAC 7 antibody HDAC 7B antibody HDAC 9 antibody HDAC 9B antibody HDAC 9FL antibody HDAC antibody HDAC7 antibody HDAC7B antibody HDAC9 antibody HDAC9_HUMAN antibody HDAC9B antibody HDAC9FL antibody HDRP antibody Histone deacetylase 4/5 related protein antibody Histone deacetylase 7 antibody Histone deacetylase 7B antibody Histone deacetylase 9 antibody Histone deacetylase 9A antibody Histone deacetylase related protein antibody Histone deacetylase-related protein antibody KIAA0744 antibody MEF2 interacting transcription repressor MITR antibody MEF2 interacting transcription repressor protein antibody MEF2-interacting transcription repressor MITR antibody MITR antibody
Molecular Weight(MW) 140 kDa
Cellular Localization Nucleus.
Database Links
SwissProt ID Q9UKV0
Application

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-HDAC9 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-HDAC9 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-HDAC9 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-HDAC9 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-HDAC9 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-HDAC9 antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-HDAC9 antibody. Counter stained with hematoxylin.
Positive Control K562, HepG2, Raji, A431, PC-3M, SH-SY5Y, human tonsil tissue, human colon cancer tissue, human kidney tissue.
Application Notes WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
IP:1:10-1:50
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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