Application
Fig1: Western blot analysis of LAMP2a on mouse placenta tissue lysates using anti-LAMP2a antibody at 1/1,000 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LAMP2a antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-LAMP2a antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-LAMP2a antibody. Counter stained with hematoxylin.| Product Name | LAMP2a |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD107 antigen-like family member B antibody CD107b antibody LAMP 2 antibody Lamp 2a antibody LAMP-2 antibody LAMP2 antibody LAMP2_HUMAN antibody Lysosome-associated membrane glycoprotein 2 antibody Lysosome-associated membrane protein 2 antibody |
| Product description | Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-1 (also designated CD107A) and LAMP-2 (also designated CD107B) are involved in a variety of functions, including cellular adhesion, and are thought to participate in the process of tumor invasion and metastasis. Newly synthesized LAMP-1 and LAMP-2 proteins are sorted at the trans Golgi network and are transported intracellularly via a pathway that is distinct from the clathrin-coated vesicles used for the mannose-6 phosphate receptor. LAMP-1 is expressed on the surface of thrombin-activated but not resting platelets, and it is thought to be involved in the adhesive, prothrombic properties of these cells. Both LAMP-1 and LAMP-2 are involved in maintaining lysosome acidity and protecting the lysosomal membranes from autodigestion, and their expression is increased in patients with lysosomal storage disorders. |
| Immunogen | Synthetic peptide within C-terminal human LAMP2a. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500 IHC:1:50-1:200 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | CD107 antigen-like family member B antibody CD107b antibody LAMP 2 antibody Lamp 2a antibody LAMP-2 antibody LAMP2 antibody LAMP2_HUMAN antibody Lysosome-associated membrane glycoprotein 2 antibody Lysosome-associated membrane protein 2 antibody |
|---|---|
| Cellular Localization | Plasma membrane. Endosome. Lysosome. |
| SwissProt ID | P13473 |
|---|
Application
Fig1: Western blot analysis of LAMP2a on mouse placenta tissue lysates using anti-LAMP2a antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LAMP2a antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-LAMP2a antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-LAMP2a antibody. Counter stained with hematoxylin.| Positive Control | Mouse placenta tissue, human prostate tissue, human kidney tissue, human placenta tissue. |
|---|---|
| Application Notes | WB:1:500 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
