Application
Fig1: Western blot analysis of IGFBP2 on Human serum (1) and NCCIT (2) lysates using anti-IGFBP2 antibody at 1/500 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-IGFBP2 antibody. Counter stained with hematoxylin.| Product Name | IGFBP2 [JU37-46] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BP 2 antibody BP2 antibody IBP 2 antibody IBP-2 antibody IBP2 antibody IBP2_HUMAN antibody IGF binding protein 2 antibody IGF BP53 antibody IGF-binding protein 2 antibody IGFBP 2 antibody IGFBP-2 antibody IGFBP2 antibody IGFBP53 antibody Insulin like growth factor binding protein 2 36kDa antibody Insulin like growth factor binding protein 2 antibody Insulin like growth factor-binding protein 2 precursor antibody Insulin-like growth factor-binding protein 2 antibody |
| Product description | The Insulin-like growth factor-binding proteins (IGFBPs), a family of homologous proteins that have co-evolved with the IGFs, serve not only as shuttle molecules for the soluble IGFs, but also confer a level of regulation to the IGF signaling system. Physical association of the IGFBPs with IGF influences the bio-availability of the growth factors, and their concentration and distribution in the extracellular environment. The IGFBPs also appear to have biological activity independent of the IGFs. Seven IGFBPs have been described, each differing in their tissue distribution, half-lives and modulation of IGF interactions with their receptors. IGFBP1 is negatively regulated by Insulin production. The IGFBP1 gene is expressed at a high level during fetal liver development and in response to nutritional changes and diabetes. IGFBP2, which may function as a chaperone, escorting IGFs to their target tissues, is expressed in several human tissues including fetal eye and fetal brain. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2,000 IHC:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | BP 2 antibody BP2 antibody IBP 2 antibody IBP-2 antibody IBP2 antibody IBP2_HUMAN antibody IGF binding protein 2 antibody IGF BP53 antibody IGF-binding protein 2 antibody IGFBP 2 antibody IGFBP-2 antibody IGFBP2 antibody IGFBP53 antibody Insulin like growth factor binding protein 2 36kDa antibody Insulin like growth factor binding protein 2 antibody Insulin like growth factor-binding protein 2 precursor antibody Insulin-like growth factor-binding protein 2 antibody |
|---|---|
| Molecular Weight(MW) | 35 kDa |
| Cellular Localization | Secreted. |
| SwissProt ID | P18065 |
|---|
Application
Fig1: Western blot analysis of IGFBP2 on Human serum (1) and NCCIT (2) lysates using anti-IGFBP2 antibody at 1/500 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-IGFBP2 antibody. Counter stained with hematoxylin.| Positive Control | Human serum lysate, NCCIT, human liver tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
