Application
Fig1: Western blot analysis of IP3 Receptor on Hela cell lysate using anti-IP3 Receptor antibody at 1/500 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-IP3 Receptor antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-IP3 Receptor antibody. Counter stained with hematoxylin.Application
Fig4: Flow cytometric analysis of SH-SY-5Y cells with IP3 Receptor antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.| Product Name | IP3 Receptor |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 4 antibody 5-trisphosphate receptor antibody 5-trisphosphate receptor type 1 antibody DKFZp313E1334 antibody DKFZp313N1434 antibody inositol 1 4 5 triphosphate receptor type 1 antibody Inositol 1 4 5 trisphosphate Receptor Type 1 antibody Inositol 1 antibody InsP3R1 antibody IP3 antibody IP3 receptor antibody IP3 receptor isoform 1 antibody IP3R 1 antibody IP3R antibody IP3R1 antibody ITPR 1 antibody Itpr1 antibody ITPR1_HUMAN antibody SCA15 antibody SCA16 antibody SCA29 antibody Type 1 inositol 1 4 5 trisphosphate receptor antibody Type 1 inositol 1 antibody Type 1 InsP3 receptor antibody |
| Product description | Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways. |
| Immunogen | Synthetic peptide within C-terminal human IP3 Receptor. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:500-1:1,000 IHC:1:50-1:200 FC:1:50-1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | 4 antibody 5-trisphosphate receptor antibody 5-trisphosphate receptor type 1 antibody DKFZp313E1334 antibody DKFZp313N1434 antibody inositol 1 4 5 triphosphate receptor type 1 antibody Inositol 1 4 5 trisphosphate Receptor Type 1 antibody Inositol 1 antibody InsP3R1 antibody IP3 antibody IP3 receptor antibody IP3 receptor isoform 1 antibody IP3R 1 antibody IP3R antibody IP3R1 antibody ITPR 1 antibody Itpr1 antibody ITPR1_HUMAN antibody SCA15 antibody SCA16 antibody SCA29 antibody Type 1 inositol 1 4 5 trisphosphate receptor antibody Type 1 inositol 1 antibody Type 1 InsP3 receptor antibody |
|---|---|
| Molecular Weight(MW) | 314 kDa |
| Cellular Localization | Cytoplasm. Cytoplasmic vesicle. Endoplasmic reticulum. Membrane. |
Application
Fig1: Western blot analysis of IP3 Receptor on Hela cell lysate using anti-IP3 Receptor antibody at 1/500 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-IP3 Receptor antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-IP3 Receptor antibody. Counter stained with hematoxylin.
Application
Fig4: Flow cytometric analysis of SH-SY-5Y cells with IP3 Receptor antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.| Positive Control | Hela, rat brain tissue, mouse brain tissue, SH-SY-5Y. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
