Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.| Product Name | CFTR |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ABC 35 antibody ABC35 antibody ABCC 7 antibody ABCC7 antibody ATP binding cassette sub family C member 7 antibody ATP Binding Cassette Superfamily C Member 7 antibody ATP binding cassette transporter sub family C member 7 antibody ATP-binding cassette sub-family C member 7 antibody cAMP dependent chloride channel antibody cAMP-dependent chloride channel antibody CF antibody CFTR antibody CFTR/MRP antibody CFTR_HUMAN antibody Channel conductance controlling ATPase antibody Channel conductance-controlling ATPase antibody Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub family C, member 7) antibody Cystic fibrosis transmembrane conductance regulator antibody Cystic fibrosis transmembrane conductance regulator ATP binding cassette sub family C member 7 antibody Cystic Fibrosis Transmembrane Regulator antibody dJ760C5.1 antibody MRP 7 antibody MRP7 antibody TNR CFTR antibody |
| Product description | EEpithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Exerts its function also by modulating the activity of other ion channels and transporters . Plays an important role in airway fluid homeostasis . Contributes to the regulation of the pH and the ion content of the airway surface fluid layer and thereby plays an important role in defense against pathogens. Modulates the activity of the epithelial sodium channel (ENaC) complex, in part by regulating the cell surface expression of the ENaC complex. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the transporter SLC4A7 . Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. |
| Immunogen | Synthetic peptide within C-terminal human CFTR. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHCFC |
| WB:1:500-1:1,000 ICC:1:50-1:500 IHC:1:50 -1:20 FC:1:50-1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ABC 35 antibody
ABC35 antibody
ABCC 7 antibody
ABCC7 antibody
ATP binding cassette sub family C member 7 antibody
ATP Binding Cassette Superfamily C Member 7 antibody
ATP binding cassette transporter sub family C member 7 antibody
ATP-binding cassette sub-family C member 7 antibody
cAMP dependent chloride channel antibody
cAMP-dependent chloride channel antibody
CF antibody
CFTR antibody
CFTR/MRP antibody
CFTR_HUMAN antibody
Channel conductance controlling ATPase antibody
Channel conductance-controlling ATPase antibody
Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub family C member 7) antibody Cystic fibrosis transmembrane conductance regulator antibody Cystic fibrosis transmembrane conductance regulator ATP binding cassette sub family C member 7 antibody Cystic Fibrosis Transmembrane Regulator antibody dJ760C5.1 antibody MRP 7 antibody MRP7 antibody TNR CFTR antibody |
|---|---|
| Molecular Weight(MW) | 168/69 kDa (Predicted band size) |
| Cellular Localization | Plasma membrane. Endoplasmic reticulum. Endosome. Nucleus. |
Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Application
Fig9: Flow cytometric analysis of SKOV-3 cells with CFTR antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.| Positive Control | LOVO, A549, rat trachea tissue, human colon tissue, human esophagus tissue, human uterine tissue, mouse pancreas tissue, SKOV-3. |
|---|---|
| Application Notes | WB:1:500-1:1,000 ICC:1:50-1:500 IHC:1:50 -1:20 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
