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MAPKAP Kinase 2 [JU30-31]

Catalog Number:OM629009
OM629009
Discount Price
OM629009-100ul
1~2 Week
100ul
OM629009-50ul
50ul
OM629009-20ul
20ul
1~2 Week
Product Profile
Product Name MAPKAP Kinase 2 [JU30-31]
Antibody Type Primary Antibodies
Antigen Alias MAP kinase activated protein Kinase 2 antibody MAP kinase-activated protein kinase 2 antibody MAPK activated protein kinase 2 antibody MAPK-activated protein kinase 2 antibody MAPK2_HUMAN antibody MAPKAP K2 antibody MAPKAP kinase 2 antibody MAPKAPK 2 antibody MAPKAPK-2 antibody MAPKAPK2 antibody Mitogen activated protein kinase activated protein kinase 2 antibody MK 2 antibody MK2 antibody
Product description The MAPKAP kinases (for MAP kinase activated protein kinases) are a group of MAP kinase substrates which are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identifed and serve as substrates for the ERK and p38 MAP kinases. These include the serine/threonine kinases Rsk-1 (also designated MAPKAP kinase-1), Rsk-2 and Rsk-3, which are phosphorylated by ERK1 and ERK2. Similarly, p38 phosphorylates and activates the serine/threonine kinases MAPKAP kinase-2 and MAPKAP kinase-3 (also designated 3pK). The serine/threonine kinases Mnk1 and Mnk2 are substrates for both ERK and p38 MAP kinases.
Immunogen Recombinant protein
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBIP
WB:1:500-1:1,000
IP:1:10-1:50
Species Reactivity HumanMouse
Concentration 1mg/ml
Target Information
Alternative Names MAP kinase activated protein Kinase 2 antibody MAP kinase-activated protein kinase 2 antibody MAPK activated protein kinase 2 antibody MAPK-activated protein kinase 2 antibody MAPK2_HUMAN antibody MAPKAP K2 antibody MAPKAP kinase 2 antibody MAPKAPK 2 antibody MAPKAPK-2 antibody MAPKAPK2 antibody Mitogen activated protein kinase activated protein kinase 2 antibody MK 2 antibody MK2 antibody
Molecular Weight(MW) 46 kDa
Cellular Localization Cytoplasm. Nucleus.
Database Links
SwissProt ID P49137 P49138
Application

Application

Fig1: Western blot analysis of MAPKAP Kinase 2 on SK-Br-3 cell lysate using anti-MAPKAP Kinase 2 antibody at 1/500 dilution.
Positive Control SK-Br-3.
Application Notes WB:1:500-1:1,000
IP:1:10-1:50
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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