Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse fallopian tubes using anti-NR1D1 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse fallopian tubes using anti-NR1D1 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse fallopian tubes using anti-NR1D1 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse fallopian tubes using anti-NR1D1 antibody. Counter stained with hematoxylin.| Product Name | NR1D1 [JU34-31] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EAR-1 antibody EAR1 antibody ERBA-related 1 antibody hRev antibody Nr1d1 antibody NR1D1_HUMAN antibody Nuclear receptor Rev ErbA alpha antibody Nuclear receptor subfamily 1 group D member 1 antibody Rev erbAalpha antibody Rev erbalpha antibody Rev-erbA-alpha antibody Rev-ErbAalpha antibody Reverba antibody THRA1 antibody THRAL antibody Thyroid hormone receptor, alpha like antibody Thyroid hormone receptor, alpha-1- like antibody V-erbA-related protein 1 antibody |
| Product description | Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the expression of core clock components ARTNL/BMAL1, CLOCK and CRY1. Also regulates genes involved in metabolic functions, including lipid and bile acid metabolism, adipogenesis, gluconeogenesis and the macrophage inflammatory response. Acts as a receptor for heme which stimulates its interaction with the NCOR1/HDAC3 corepressor complex, enhancing transcriptional repression. Recognizes two classes of DNA response elements within the promoter of its target genes and can bind to DNA as either monomers or homodimers, depending on the nature of the response element. Binds as a monomer to a response element composed of the consensus half-site motif 5'-[A/G]GGTCA-3' preceded by an A/T-rich 5' sequence (RevRE), or as a homodimer to a direct repeat of the core motif spaced by two nucleotides (RevDR-2). |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:1,000 IHC:1:100 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | EAR-1 antibody
EAR1 antibody
ERBA-related 1 antibody
hRev antibody
Nr1d1 antibody
NR1D1_HUMAN antibody
Nuclear receptor Rev ErbA alpha antibody
Nuclear receptor subfamily 1 group D member 1 antibody
Rev erbAalpha antibody
Rev erbalpha antibody
Rev-erbA-alpha antibody
Rev-ErbAalpha antibody
Reverba antibody
THRA1 antibody
THRAL antibody
Thyroid hormone receptor alpha like antibody Thyroid hormone receptor alpha-1- like antibody V-erbA-related protein 1 antibody |
|---|---|
| Molecular Weight(MW) | 67 kDa |
| Cellular Localization | Nucleus. Cytoplasm. |
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse fallopian tubes using anti-NR1D1 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse fallopian tubes using anti-NR1D1 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse fallopian tubes using anti-NR1D1 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse fallopian tubes using anti-NR1D1 antibody. Counter stained with hematoxylin.| Positive Control | HepG2, SiHa, Human liver tissue, human colon cancer tissue, human uterus tissue, mouse fallopian tubes tissue. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IHC:1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
