Application
s of IL12B on different lysates using anti-IL12B antibody at 1/500 dilution. Positive control： Lane1: Hela Lane2: Mouse placenta| Product Name | IL12B |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CLMF antibody CLMF p40 antibody CLMF2 antibody Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody IL 12B antibody IL-12 subunit p40 antibody IL-12B antibody IL12 p40 antibody IL12B antibody IL12B_HUMAN antibody IMD28 antibody IMD29 antibody Interleukin 12 beta chain antibody Interleukin 12 p40 antibody Interleukin-12 subunit beta antibody NK cell stimulatory factor chain 2 antibody NKSF antibody NKSF2 antibody |
| Product description | Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
| Immunogen | Synthetic peptide within mouse IL12B 220-300 aa. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:1,000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | CLMF antibody CLMF p40 antibody CLMF2 antibody Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody IL 12B antibody IL-12 subunit p40 antibody IL-12B antibody IL12 p40 antibody IL12B antibody IL12B_HUMAN antibody IMD28 antibody IMD29 antibody Interleukin 12 beta chain antibody Interleukin 12 p40 antibody Interleukin-12 subunit beta antibody NK cell stimulatory factor chain 2 antibody NKSF antibody NKSF2 antibody |
|---|---|
| Molecular Weight(MW) | 37 kDa |
| Cellular Localization | Secreted. |
Application
s of IL12B on different lysates using anti-IL12B antibody at 1/500 dilution. Positive control： Lane1: Hela Lane2: Mouse placenta| Positive Control | Hela, Mouse placenta tissue lysate. |
|---|---|
| Application Notes | WB:1:500-1:1,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
