Application
Fig1: Western blot analysis of SF3B1 on different lysates using anti-SF3B1 antibody at 1/500 dilution. Positive control: Lane 1: Mouse thymus Lane 2: HelaApplication
Fig2: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-SF3B1 antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-SF3B1 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-SF3B1 antibody. Counter stained with hematoxylin.Application
Fig5: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-SF3B1 antibody. Counter stained with hematoxylin.Application
Fig6: Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue using anti-SF3B1 antibody. Counter stained with hematoxylin.| Product Name | SF3B1 [JB40-32] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Hsh 155 antibody MDS antibody Pre mRNA processing 10 antibody Pre mRNA splicing factor SF3b 155 kDa subunit antibody PRP 10 antibody PRP10 antibody PRPF 10 antibody PRPF10 antibody SAP 155 antibody SAP155 antibody SF3B 1 antibody SF3b155 antibody Spliceosome associated protein 155 antibody Splicing factor 3b subunit 1 155kDa antibody Splicing factor 3B subunit 1 antibody |
| Product description | Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCICCIFFC |
| WB:1:500-1:2,000 IHC:1:50-1:200 ICC:1:50 FC:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | Hsh 155 antibody MDS antibody Pre mRNA processing 10 antibody Pre mRNA splicing factor SF3b 155 kDa subunit antibody PRP 10 antibody PRP10 antibody PRPF 10 antibody PRPF10 antibody SAP 155 antibody SAP155 antibody SF3B 1 antibody SF3b155 antibody Spliceosome associated protein 155 antibody Splicing factor 3b subunit 1 155kDa antibody Splicing factor 3B subunit 1 antibody |
|---|---|
| Molecular Weight(MW) | 146 kDa |
| Cellular Localization | Nucleus. |
Application
Fig1: Western blot analysis of SF3B1 on different lysates using anti-SF3B1 antibody at 1/500 dilution. Positive control: Lane 1: Mouse thymus Lane 2: Hela
Application
Fig2: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-SF3B1 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-SF3B1 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-SF3B1 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-SF3B1 antibody. Counter stained with hematoxylin.
Application
Fig6: Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue using anti-SF3B1 antibody. Counter stained with hematoxylin.| Positive Control | Mouse thymus tissue lysate, Hela, human colon cancer tissue, human skin tissue, human kidney tissue, mouse small intestine tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:200 ICC:1:50 FC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
