Application
Fig1: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Versican antibody. Counter stained with hematoxylin.Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Versican antibody. Counter stained with hematoxylin.| Product Name | Versican [JB42-32] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Chondroitin sulfate proteoglycan 2 antibody Chondroitin sulfate proteoglycan core protein 2 antibody Chondroitin sulfate proteoglycan core protein, cartilage antibody CSPG2 antibody CSPG2_HUMAN antibody ERVR antibody GHAP antibody Glial hyaluronate binding protein antibody Glial hyaluronate-binding protein antibody Large fibroblast proteoglycan antibody PG-M antibody PGM antibody VCAN antibody Versican antibody Versican core protein antibody Versican proteoglycan antibody WGN 1 antibody WGN antibody WGN1 antibody |
| Product description | Versican (chondroitin sulfate proteoglycan 2) is a large extracellular matrix proteoglycan involved in cell growth and differentiation. Important as a structural molecule, versican creates loose and hydrated matrices during key events in development and disease. The protein contains hyaluronic acid and glycosminoglycan-binding domains, epidermal growth factor-like repeats, a lectin-like sequence and a complement regulatory protein-like domain. Splice variants differ greatly in length and degree of modification by glycosaminoglycan chains. Accumulation around smooth muscle cells in lesions of atherosclerosis, suggests a role for versican in atherogenesis. Versican, differentially expressed in human melanoma, plays a role in tumor development and may be a reliable marker for clinical diagnosis. The organization of HA- and versican-rich pericellular matrices may faciliatate migration and mitosis by diminishing cell surface adhesivity and affecting cell shape through steric exclusion and the viscous properties of HA proteoglycan gels. The human verisican gene maps to chromosome 5q14.3. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | IHCWB |
| IHC:1:50-1:200 WB:1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | Chondroitin sulfate proteoglycan 2 antibody
Chondroitin sulfate proteoglycan core protein 2 antibody
Chondroitin sulfate proteoglycan core protein cartilage antibody CSPG2 antibody CSPG2_HUMAN antibody ERVR antibody GHAP antibody Glial hyaluronate binding protein antibody Glial hyaluronate-binding protein antibody Large fibroblast proteoglycan antibody PG-M antibody PGM antibody VCAN antibody Versican antibody Versican core protein antibody Versican proteoglycan antibody WGN 1 antibody WGN antibody WGN1 antibody |
|---|---|
| Molecular Weight(MW) | 373/265/182/74 kDa |
| Cellular Localization | Extracellular matrix. Secreted. |
Application
Fig1: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Versican antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Versican antibody. Counter stained with hematoxylin.| Positive Control | Human spleen tissue, mouse brain tissue. |
|---|---|
| Application Notes | IHC:1:50-1:200 WB:1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
