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DNA Ligase I [JB43-39]

Catalog Number:OM629062
OM629062
Discount Price
OM629062-100ul
1~2 Week
100ul
OM629062-50ul
50ul
OM629062-20ul
20ul
1~2 Week
Product Profile
Product Name DNA Ligase I [JB43-39]
Antibody Type Primary Antibodies
Antigen Alias DNA ligase 1 antibody DNA ligase I antibody DNLI1_HUMAN antibody LIG 1 antibody lig1 antibody Ligase I DNA ATP dependent antibody MGC117397 antibody MGC130025 antibody Polydeoxyribonucleotide synthase [ATP] 1 antibody
Product description This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
Immunogen Recombinant protein within C terminal human DNA Ligase.
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBIHC
WB:1:500
IHC:1:50-1:200
Species Reactivity HumanRat
Concentration 1mg/ml
Target Information
Alternative Names DNA ligase 1 antibody DNA ligase I antibody DNLI1_HUMAN antibody LIG 1 antibody lig1 antibody Ligase I DNA ATP dependent antibody MGC117397 antibody MGC130025 antibody Polydeoxyribonucleotide synthase [ATP] 1 antibody
Molecular Weight(MW) Predicted band size 102 kDa
Cellular Localization Nucleus.
Database Links
SwissProt ID P18858 37227
Application

Application

Fig1: Western blot analysis of DNA Ligase I on different cell lysates using anti-DNA Ligase I antibody at 1/500 dilution. Positive control: Lane 1: Daudi Lane 2: A431 Lane 3: MCF-7

Application

Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-DNA Ligase I antibody. Counter stained with hematoxylin.

Application

Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-DNA Ligase I antibody. Counter stained with hematoxylin.

Application

Fig4: Immunohistochemical analysis of paraffin-embedded rat testis tissue using anti-DNA Ligase I antibody. Counter stained with hematoxylin.
Positive Control Daudi, A431, MCF-7, Rat testis tissue, human tonsil tissue, human spleen tissue.
Application Notes WB:1:500
IHC:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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