Application
Fig1: ICC staining CaV2.3 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig2: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-CaV2.3 antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-CaV2.3 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-CaV2.3 antibody. Counter stained with hematoxylin.Application
Fig5: Flow cytometric analysis of 293T cells with CaV2.3 antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.| Product Name | CaV2.3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | alpha-1 polypeptide antibody BII antibody Brain calcium channel II antibody CAC 1E antibody CAC1E antibody CAC1E_HUMAN antibody CACH 6 antibody CACH6 antibody CACNA1E antibody Cacnl1 a6 antibody CACNL1A6 antibody Calcium channel antibody Calcium channel, L type, alpha 1 polypeptide, isoform 6 antibody calcium channel, R type antibody Cav 2.3 antibody Cchra 1 antibody Cchra1 antibody isoform 6 antibody L type antibody Voltage dependent R type calcium channel subunit alpha 1E antibody Voltage gated calcium channel subunit alpha Cav2.3 antibody Voltage-dependent R-type calcium channel subunit alpha-1E antibody Voltage-gated calcium channel subunit alpha Cav2.3 antibody |
| Product description | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel. They are however insensitive to dihydropyridines (DHP). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing. |
| Immunogen | Synthetic peptide within rat CaV2.3 aa 860-910. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHCFC |
| WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | alpha-1 polypeptide antibody
BII antibody
Brain calcium channel II antibody
CAC 1E antibody
CAC1E antibody
CAC1E_HUMAN antibody
CACH 6 antibody
CACH6 antibody
CACNA1E antibody
Cacnl1 a6 antibody
CACNL1A6 antibody
Calcium channel antibody
Calcium channel L type alpha 1 polypeptide isoform 6 antibody calcium channel R type antibody Cav 2.3 antibody Cchra 1 antibody Cchra1 antibody isoform 6 antibody L type antibody Voltage dependent R type calcium channel subunit alpha 1E antibody Voltage gated calcium channel subunit alpha Cav2.3 antibody Voltage-dependent R-type calcium channel subunit alpha-1E antibody Voltage-gated calcium channel subunit alpha Cav2.3 antibody |
|---|---|
| Molecular Weight(MW) | 262 kDa |
| Cellular Localization | Membrane. |
Application
Fig1: ICC staining CaV2.3 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-CaV2.3 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-CaV2.3 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-CaV2.3 antibody. Counter stained with hematoxylin.
Application
Fig5: Flow cytometric analysis of 293T cells with CaV2.3 antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.| Positive Control | Rat brain tissue, human kidney tissue, human placenta tissue, mouse brain tissue, 293T. |
|---|---|
| Application Notes | WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
