Application
Fig1: Western blot analysis of Fusion glycoprotein F0 on Fusion glycoprotein F0 transfected HEK293 cell lysates using anti- Fusion glycoprotein F0 antibody at 1/500 dilution.| Product Name | Fusion glycoprotein F0 Rabbit Polyclonal Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | During virus entry, induces fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. The fusogenic activity is inactive untill entry into host cell endosome, where a furin-like protease cleaves off a small peptide between F1 and F2. Interacts directly with heparan sulfate and may participate in virus attachment. Furthermore, the F2 subunit was identifed as the major determinant of RSV host cell specificity. Later in infection, proteins F expressed at the plasma membrane of infected cells can mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis. The fusion protein is also able to trigger p53-dependent apoptosis. |
| Immunogen | Synthetic peptide within newcastle disease virus Fusion glycoprotein F0 aa 504-553 / 553. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFWB |
| WB:1:500-1,000 ELISA:1:5,000-1:10,000 |
|
| Species Reactivity | Avian |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | Fusion glycoprotein F0 antibody Fusion glycoprotein F1 antibody Fusion glycoprotein F2 antibody Fusion protein (F) antibody RSV fusion protein antibody |
|---|---|
| Molecular Weight(MW) | 59 kDa |
| Cellular Localization | SwissProt: W8CLH7 (Avian avulavirus 1) |
| SwissProt ID | W8CLH7 |
|---|
Application
Fig1: Western blot analysis of Fusion glycoprotein F0 on Fusion glycoprotein F0 transfected HEK293 cell lysates using anti- Fusion glycoprotein F0 antibody at 1/500 dilution.| Positive Control | Fusion glycoprotein F0 transfected HEK293 cell. |
|---|---|
| Application Notes | WB:1:500-1,000 ELISA:1:5,000-1:10,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
