Application
Fig1: Western blot analysis of RBPJK on human colon tissue lysates using anti-RBPJK antibody at 1/500 dilution.| Product Name | RBPJK [JB49-34] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AI843960 antibody AOS3 antibody CBF 1 antibody CBF-1 antibody CBF1 antibody csl antibody IGKJRB antibody IGKJRB1 antibody J kappa recombination signal binding protein antibody J kappa-recombination signal-binding protein antibody KBF2 antibody NY REN 30 antigen antibody RBP J antibody RBP J kappa antibody RBP JK antibody RBP-J antibody RBP-J kappa antibody RBP-JK antibody Rbpj antibody RBPJK antibody RBPSUH antibody recombination signal binding protein for immunoglobulin kappa J region antibody Recombining binding protein suppressor of hairless antibody Renal carcinoma antigen NY-REN-30 antibody SUH antibody SUH_HUMAN antibody |
| Product description | Recombination signal binding protein Jκ (RBP-Jκ), also designated KBF2 or CBF1, is the mammalian homolog of the Drosophila suppressor of hairless (Su(H)), a protein involved in the development of the peripheral nervous system. RBP-Jκ is ubiquitously expressed in mammalian tissues and is involved in the regulation of gene expression. RBP-Jκ has been shown to directly interact with the intercellular domain of the cell surface receptor Notch 1. Proteolytically cleaved Notch 1 translocates to the nucleus, where it binds DNA-bound RBP-Jκ and activates transcription of target genes. These genes include NFκB p52 and the Epstein-Barr virus (EBV) protein EBNA-2, both of which contain RBP-Jκ-binding sequences within their promoter regions. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WB |
| WB:1:1,000-1:5,000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | AI843960 antibody AOS3 antibody CBF 1 antibody CBF-1 antibody CBF1 antibody csl antibody IGKJRB antibody IGKJRB1 antibody J kappa recombination signal binding protein antibody J kappa-recombination signal-binding protein antibody KBF2 antibody NY REN 30 antigen antibody RBP J antibody RBP J kappa antibody RBP JK antibody RBP-J antibody RBP-J kappa antibody RBP-JK antibody Rbpj antibody RBPJK antibody RBPSUH antibody recombination signal binding protein for immunoglobulin kappa J region antibody Recombining binding protein suppressor of hairless antibody Renal carcinoma antigen NY-REN-30 antibody SUH antibody SUH_HUMAN antibody |
|---|---|
| Molecular Weight(MW) | 55 kDa |
| Cellular Localization | Cytoplasm. Nucleus. |
| SwissProt ID | Q06330 |
|---|
Application
Fig1: Western blot analysis of RBPJK on human colon tissue lysates using anti-RBPJK antibody at 1/500 dilution.| Positive Control | Human colon tissue lysate. |
|---|---|
| Application Notes | WB:1:1,000-1:5,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
