Application
Fig1: Western blot analysis of SRC1 on K562 cell lysate using anti- SRC1 antibody at 1/2,000 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-SRC1 antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human thyroid gland tissue using anti-SRC1 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded human breast tissue using anti- SRC1 antibody. Counter stained with hematoxylin.| Product Name | SRC1 [JB66-31] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | bHLHe74 antibody Class E basic helix-loop-helix protein 74 antibody F SRC 1 antibody Hin 2 protein antibody Hin2 protein antibody MGC129719 antibody MGC129720 antibody mNRC 1 antibody NCoA 1 antibody NCoA-1 antibody Ncoa1 antibody NCOA1_HUMAN antibody Nuclear receptor coactivator 1 antibody Nuclear receptor coactivator protein 1 antibody NY REN 52 antigen antibody Protein Hin 2 antibody Protein Hin-2 antibody Protein Hin2 antibody Renal carcinoma antigen NY REN 52 antibody Renal carcinoma antigen NY-REN-52 antibody RIP 160 antibody RIP160 antibody SRC 1 antibody SRC-1 antibody Steroid receptor coactivator 1 antibody |
| Product description | Nuclear receptors for steroids, thyroid hormones and retinoic acids are ligand-dependent transcription factors that activate transcription through specific DNA binding sites in their target genes. Several related transcriptional coactivators and corepressors have been described that work in concert with the steroid receptor family to either induce or repress transcription from hormone-responsive elements. This family includes GRIP1 (for GR interacting protein 1, also designated NCoA-2 or Tif2); SRC-1 (for steroid receptor coactivator-1, also designated NCoA-1); RAC3 (also designated AIB1, for amplified in breast cancer, or ACTR), which displays elevated expression in estrogen receptor positive ovarian and breast cancers; and p/CIP (for p300/CBP/Co-Integrator Protein), which is required for the transcriptional activation of p300/CBP-dependent transcription factors |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCIP |
| WB:1:500-1:2,000 IHC:1:50-1:100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | bHLHe74 antibody Class E basic helix-loop-helix protein 74 antibody F SRC 1 antibody Hin 2 protein antibody Hin2 protein antibody MGC129719 antibody MGC129720 antibody mNRC 1 antibody NCoA 1 antibody NCoA-1 antibody Ncoa1 antibody NCOA1_HUMAN antibody Nuclear receptor coactivator 1 antibody Nuclear receptor coactivator protein 1 antibody NY REN 52 antigen antibody Protein Hin 2 antibody Protein Hin-2 antibody Protein Hin2 antibody Renal carcinoma antigen NY REN 52 antibody Renal carcinoma antigen NY-REN-52 antibody RIP 160 antibody RIP160 antibody SRC 1 antibody SRC-1 antibody Steroid receptor coactivator 1 antibody |
|---|---|
| Molecular Weight(MW) | 156 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | Q15788 |
|---|
Application
Fig1: Western blot analysis of SRC1 on K562 cell lysate using anti- SRC1 antibody at 1/2,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-SRC1 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human thyroid gland tissue using anti-SRC1 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human breast tissue using anti- SRC1 antibody. Counter stained with hematoxylin.| Positive Control | K562, human lung cancer tissue, human thyroid gland tissue, human breast tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
