Application
Fig1: Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue using anti-H Cadherin antibody. Counter stained with hematoxylin.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-H Cadherin antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human fetal skeletal muscle tissue using anti-H Cadherin antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-H Cadherin antibody. Counter stained with hematoxylin.| Product Name | H Cadherin [JB14-48] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CAD13_HUMAN antibody Cadherin-13 antibody CDH13 antibody CDHH antibody H-cadherin antibody Heart cadherin antibody P105 antibody T cad antibody T Cadherin antibody T-cad antibody T-cadherin antibody Truncated cadherin antibody |
| Product description | Cadherins comprise a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogen-esis. Cadherins each contain a large extracellular domains characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as β-catenin, to regulate cadherin function. T-cadherin (for truncated-cadherin), also designated heart-cadherin or cadherin-13) expression levels have been shown to be reduced in human breast cancers and carcinoma cell lines. Evidence suggests that decreased levels of T-cadherin indicate a progression in breast malignancies. |
| Immunogen | Recombinant protein within human H Cadherin aa 1-200. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | IHCWB |
| IHC:1:50-1:200 WB:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | CAD13_HUMAN antibody Cadherin-13 antibody CDH13 antibody CDHH antibody H-cadherin antibody Heart cadherin antibody P105 antibody T cad antibody T Cadherin antibody T-cad antibody T-cadherin antibody Truncated cadherin antibody |
|---|---|
| Molecular Weight(MW) | 78 kDa |
| Cellular Localization | Cell membrane. |
Application
Fig1: Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue using anti-H Cadherin antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-H Cadherin antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human fetal skeletal muscle tissue using anti-H Cadherin antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-H Cadherin antibody. Counter stained with hematoxylin.| Positive Control | Rat skeletal muscle tissue, human kidney tissue, human fetal skeletal muscle tissue, mouse heart tissue. |
|---|---|
| Application Notes | IHC:1:50-1:200 WB:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
