Application
Fig1: Western blot analysis of DEK on A431 cell lysate using anti-DEK antibody at 1/500 dilution.| Product Name | DEK [JB36-32] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | D6S231E antibody Dek antibody DEK gene antibody DEK oncogene antibody DEK oncogene DNA binding antibody DEK_HUMAN antibody Protein DEK antibody |
| Product description | The mammalian nuclear phosphoprotein DEK is implicated in multiple cellular processes, including transcriptional regulation, mRNA processing, and chromatin remodeling, and is associated with a number of clinical autoimmune and neoplastic conditions. DEK, an abundant chromatin-associated protein, changes the topology of DNA in chromatin in vitro. Although first identified in a fusion with the CAN/Nup214 nucleoporin protein in a specific subtype of acute myelogenous leukemia, DEK is also an autoantigen in patients with Pauciarticular onset juvenile rheumatoid arthritis. Furthermore, the last 65 amino acids of DEK can partially reverse the mutation-prone phenotype of cells from patients with ataxia-telangiectasia. The human DEK gene maps to chromosome 6p22.3. |
| Immunogen | Recombinant protein corresponding to C-terminal human DEK. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIP |
| WB:1:500-1:1,000 IP:1:50-1:100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | D6S231E antibody Dek antibody DEK gene antibody DEK oncogene antibody DEK oncogene DNA binding antibody DEK_HUMAN antibody Protein DEK antibody |
|---|---|
| Molecular Weight(MW) | 43 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | P35659 |
|---|
Application
Fig1: Western blot analysis of DEK on A431 cell lysate using anti-DEK antibody at 1/500 dilution.| Positive Control | A431. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IP:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
