Application
Fig1: Western blot analysis of PON2 on A549 cell lysate using anti-PON2 antibody at 1/1,000 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-PON2 antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human appendix tissue using anti-PON2 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PON2 antibody. Counter stained with hematoxylin.Application
Fig5: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-PON2 antibody. Counter stained with hematoxylin.| Product Name | PON2 [JG35-80] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | A esterase 2 antibody A-esterase 2 antibody Aromatic esterase 2 antibody Paraoxonase 2 antibody Paraoxonase nirs antibody PON 2 antibody PON2 antibody PON2_HUMAN antibody Serum aryldialkylphosphatase 2 antibody Serum paraoxonase/arylesterase 2 antibody |
| Product description | Paroxon is an organophosphorus anticholinesterase compound, used topically in the treatment of glaucoma. It is produced in vivo in mammals by microsomal oxidation of the insecticide parathion. Parathion is inert until transformed to paroxon. Paroxonase (paraoxonase or PON) is an arylesterase that is capable of hydrolyzing paroxon to produce p-nitrophenol. PONs are nonspecific and their classification is based not only on substrate specificity but also on tissue distribution, inhibition properties, and physicochemical characteristics such as electrophoretic mobility and molecular weight. In contrast to PON1, which is expressed mainly in the liver, PON2 is expressed in a variety of mouse tissues, including the pancreas. PON3 is associated with the high density lipoprotein fraction of serum. The genes which encode PON1-3 are physically linked and map to human chromosome 7q21.3. |
| Immunogen | Recombinant protein within human PON2 aa 200-350. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCIP |
| WB:1:500-1:2,000 IP:1:10-1:50 IHC:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | A esterase 2 antibody A-esterase 2 antibody Aromatic esterase 2 antibody Paraoxonase 2 antibody Paraoxonase nirs antibody PON 2 antibody PON2 antibody PON2_HUMAN antibody Serum aryldialkylphosphatase 2 antibody Serum paraoxonase/arylesterase 2 antibody |
|---|---|
| Molecular Weight(MW) | 38/39 kDa |
| Cellular Localization | Membrane. |
Application
Fig1: Western blot analysis of PON2 on A549 cell lysate using anti-PON2 antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-PON2 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human appendix tissue using anti-PON2 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PON2 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-PON2 antibody. Counter stained with hematoxylin.| Positive Control | A549, human colon cancer tissue, human appendix tissue, human kidney tissue, mouse testis tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IP:1:10-1:50 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
