Application
Fig1: Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-Activin A Receptor Type IC (ER1903-22) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53 kDApplication
Fig2: Sample: Placenta (Mouse) Lysate at 40 ug Primary: Anti-Activin A Receptor Type IC (ER1903-22) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53 kDApplication
Fig3: Sample: HepG2(Human) Cell Lysate at 30 ug Hela(Human) Cell Lysate at 30 ug Primary: Anti-Activin A Receptor Type IC (ER1903-22) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53 kDApplication
Fig4: Blank control: H9C2 (blue) Isotype Control Antibody: Rabbit IgG(orange) ; Secondary Antibody: Goat anti-rabbit IgG-FITC(white blue), Dilution: 1:100 in 1 X PBS containing 0.5% BSA ; Primary Antibody Dilution: 3μl in 100 μL1X PBS containing 0.5% BSA(green).| Product Name | Activin A Receptor Type IC |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Activin A receptor, type IC Activin receptor like kinase 7 Activin receptor type 1C precursor Activin receptor type IC Activin receptor type-1C Activin receptor-like kinase 7 ACTR IC ACTR-IC ACTRIC ACV1C_HUMAN Acvr1c ACVRLK7 ALK 7 ALK-7 ALK7. |
| Product description | Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis. |
| Immunogen | KLH conjugated synthetic peptide derived from human ACTRIC/Activin A Receptor Type IC 21-120/493 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:500-2000: FC:3μg/Test: |
|
| Species Reactivity | HumanMouseRatDogPigCowRabbit |
| Concentration | 1mg/ml |
| Alternative Names | Activin A receptor type IC Activin receptor like kinase 7 Activin receptor type 1C precursor Activin receptor type IC Activin receptor type-1C Activin receptor-like kinase 7 ACTR IC ACTR-IC ACTRIC ACV1C_HUMAN Acvr1c ACVRLK7 ALK 7 ALK-7 ALK7. |
|---|---|
| Molecular Weight(MW) | 53 KDa |
| Cellular Localization | Membrane; Single-pass type I membrane protein. |
| SwissProt ID | Q8NER5 |
|---|
Application
Fig1: Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-Activin A Receptor Type IC (ER1903-22) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53 kD
Application
Fig2: Sample: Placenta (Mouse) Lysate at 40 ug Primary: Anti-Activin A Receptor Type IC (ER1903-22) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53 kD
Application
Fig3: Sample: HepG2(Human) Cell Lysate at 30 ug Hela(Human) Cell Lysate at 30 ug Primary: Anti-Activin A Receptor Type IC (ER1903-22) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53 kD
Application
Fig4: Blank control: H9C2 (blue) Isotype Control Antibody: Rabbit IgG(orange) ; Secondary Antibody: Goat anti-rabbit IgG-FITC(white blue), Dilution: 1:100 in 1 X PBS containing 0.5% BSA ; Primary Antibody Dilution: 3μl in 100 μL1X PBS containing 0.5% BSA(green).| Positive Control | Present in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy. |
|---|---|
| Application Notes | WB:1:500-2000: FC:3μg/Test: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
