Application
Fig1: Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-ADAMTS4 (ER1903-31) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 90 kD Observed band size: 100 kD| Product Name | ADAMTS4 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADAMTS 4 A disintegrin and metalloproteinase with thrombospondin motifs 4 A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 4 A disintegrin like and metalloprotease with thrombospondin type 1 motif 4 ADAM metallopeptidase with thrombospondin type 1 motif 4 ADAM TS 4 ADAM TS4 ADAMTS 2 ADAMTS2 ADAMTS4 protein ADMP 1 ADMP1 Aggrecanase 1 Aggrecanase1 KIAA0688. |
| Product description | Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu- -Ala-393' site. |
| Immunogen | KLH conjugated synthetic peptide derived from human ADAMTS4 501-839/839 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatCowRabbitSheep |
| Concentration | 1mg/ml |
| Alternative Names | ADAMTS 4 A disintegrin and metalloproteinase with thrombospondin motifs 4 A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 4 A disintegrin like and metalloprotease with thrombospondin type 1 motif 4 ADAM metallopeptidase with thrombospondin type 1 motif 4 ADAM TS 4 ADAM TS4 ADAMTS 2 ADAMTS2 ADAMTS4 protein ADMP 1 ADMP1 Aggrecanase 1 Aggrecanase1 KIAA0688. |
|---|---|
| Molecular Weight(MW) | 90 KDa |
| Cellular Localization | Secreted > extracellular space > extracellular matrix. |
| SwissProt ID | O75173 |
|---|
Application
Fig1: Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-ADAMTS4 (ER1903-31) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 90 kD Observed band size: 100 kD| Positive Control | Expressed in brain, lung and heart. Expressed at very low level in placenta and skeletal muscles. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
