Application
Fig1: Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-ADRA1B (ER1903-46) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57kD Observed band size: 60kD| Product Name | ADRA1B |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADA1B_HUMAN ADRA1 ALPHA1BAR Alpha-1B adrenergic receptor Alpha-1B adrenoreceptor Alpha-1B adrenoceptor alpha-1B-adrenergic receptor adrenergic, alpha-1B-, receptor. |
| Product description | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes. |
| Immunogen | KLH conjugated synthetic peptide derived from human ADRA1B 1-100/520 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatChickenDogPigCowHorseRabbitSheepGuinea Pig |
| Concentration | 1mg/ml |
| Alternative Names | ADA1B_HUMAN
ADRA1
ALPHA1BAR
Alpha-1B adrenergic receptor
Alpha-1B adrenoreceptor
Alpha-1B adrenoceptor
alpha-1B-adrenergic receptor
adrenergic alpha-1B- receptor. |
|---|---|
| Molecular Weight(MW) | 57 KDa |
| Cellular Localization | Nucleus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes. |
| SwissProt ID | P35368 |
|---|
Application
Fig1: Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-ADRA1B (ER1903-46) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57kD Observed band size: 60kD| Application Notes | WB:1:500-2000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
