Application
Fig1: Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti- Annexin A7 (ER1903-73)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kD Observed band size: 54 kD| Product Name | Annexin A7 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Annexin VII AnnexinVII Annexin A7 ANX7 ANXA7 SNX Synexin Annexin-7 ANXA7_HUMAN. |
| Product description | Retains NFE2L2/NRF2 in the cytosol. Functions as substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. May also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome. |
| Immunogen | KLH conjugated synthetic peptide derived from human Annexin A7 251-350/488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatDogPigCowRabbit |
| Concentration | 1mg/ml |
| Alternative Names | Annexin VII AnnexinVII Annexin A7 ANX7 ANXA7 SNX Synexin Annexin-7 ANXA7_HUMAN. |
|---|---|
| Molecular Weight(MW) | 54 KDa |
| Cellular Localization | Cytoplasm. Nucleus. Note=Shuttles between cytoplasm and nucleus. |
| SwissProt ID | Q9DBP0 |
|---|
Application
Fig1: Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti- Annexin A7 (ER1903-73)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kD Observed band size: 54 kD| Positive Control | Broadly expressed, with highest levels in skeletal muscle. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
