Application
Fig1: Sample: Brain (Mouse) Lysate at 40 ug Primary: Anti-APLP1 (ER1903-77 )at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 68 kD Observed band size: 68 kD| Product Name | APLP1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AMYLOID BETA A4 PRECURSOR-LIKE PROTEIN 1 AMYLOID PRECURSOR-LIKE PROTEIN Amyloid-like protein 1 precursor APLP 1 APLP APLP-1 Aplp1 APLP1_HUMAN C30. |
| Product description | May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. ;The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis (By similarity). |
| Immunogen | KLH conjugated synthetic peptide derived from human APLP1 1-100/650 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatDogCowHorseSheep |
| Concentration | 1mg/ml |
| Alternative Names | AMYLOID BETA A4 PRECURSOR-LIKE PROTEIN 1 AMYLOID PRECURSOR-LIKE PROTEIN Amyloid-like protein 1 precursor APLP 1 APLP APLP-1 Aplp1 APLP1_HUMAN C30. |
|---|---|
| Molecular Weight(MW) | 68 KDa |
| Cellular Localization | Cell membrane and Cytoplasm. C-terminally processed in the Golgi complex. |
| SwissProt ID | P51693 |
|---|
Application
Fig1: Sample: Brain (Mouse) Lysate at 40 ug Primary: Anti-APLP1 (ER1903-77 )at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 68 kD Observed band size: 68 kD| Positive Control | Expressed in the cerebral cortex where it is localized to the postsynaptic density (PSD). |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
