Application
Fig1: Western blot analysis of Gemin 1 on SiHa cell lysates using anti-Gemin 1 at 1/500 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded rat testis tissue using anti-Gemin 1 antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Gemin 1 antibody. Counter stained with hematoxylin.| Product Name | Gemin 1 [JG38-19] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BCD541 antibody Component of gems 1 antibody Gemin 1 antibody Gemin-1 antibody OTTHUMP00000125198 antibody OTTHUMP00000223567 antibody OTTHUMP00000223568 antibody OTTHUMP00000224066 antibody OTTHUMP00000226924 antibody SMA 1 antibody SMA 2 antibody SMA 3 antibody SMA 4 antibody SMA antibody SMA@ antibody SMA1 antibody SMA2 antibody SMA3 antibody SMA4 antibody SMN antibody SMN_HUMAN antibody SMN1 antibody SMN2 antibody SMNT antibody Survival motor neuron protein antibody Survival of motor neuron 1, telomeric antibody T-BCD541 antibody |
| Product description | The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Ensures the correct splicing of U12 intron-containing genes that may be important for normal motor and proprioceptive neurons development. Also required for resolving RNA-DNA hybrids created by RNA polymerase II, that form R-loop in transcription terminal regions, an important step in proper transcription termination. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs). |
| Immunogen | Recombinant protein within human Gemin 1 aa 1-200. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCIP |
| WB:1:500-1:1,000 IHC:1:50-1:200 IP:1:10-1:50 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | BCD541 antibody
Component of gems 1 antibody
Gemin 1 antibody
Gemin-1 antibody
OTTHUMP00000125198 antibody
OTTHUMP00000223567 antibody
OTTHUMP00000223568 antibody
OTTHUMP00000224066 antibody
OTTHUMP00000226924 antibody
SMA 1 antibody
SMA 2 antibody
SMA 3 antibody
SMA 4 antibody
SMA antibody
SMA@ antibody
SMA1 antibody
SMA2 antibody
SMA3 antibody
SMA4 antibody
SMN antibody
SMN_HUMAN antibody
SMN1 antibody
SMN2 antibody
SMNT antibody
Survival motor neuron protein antibody
Survival of motor neuron 1 telomeric antibody T-BCD541 antibody |
|---|---|
| Molecular Weight(MW) | 32 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | Q16637 |
|---|
Application
Fig1: Western blot analysis of Gemin 1 on SiHa cell lysates using anti-Gemin 1 at 1/500 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded rat testis tissue using anti-Gemin 1 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Gemin 1 antibody. Counter stained with hematoxylin.| Positive Control | SiHa, rat testis tissue, mouse brain tissue. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IHC:1:50-1:200 IP:1:10-1:50 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
