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ARC

Catalog Number:OM629414
OM629414
Discount Price
OM629414-100ul
1~2 Week
100ul
OM629414-50ul
50ul
OM629414-20ul
20ul
1~2 Week
Product Profile
Product Name ARC
Antibody Type Primary Antibodies
Antigen Alias ARG3.1 Arc Arg 3.1 Activity regulated cytoskeletal associated protein Activity regulated cytoskeletal protein Activity-regulated cytoskeleton-associated protein Activity regulated cytoskeletal-associated protein ARC/ARG3.1 Activity-regulated gene 3.1 protein homolog Activity regulated gene 3.1 protein homolog Arg3.1 KIAA0278 ARC_HUMAN growth factor ARC.
Product description Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.
Immunogen KLH conjugated synthetic peptide derived from human ARC 101-200/396
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBFC
WB:1:500-2000:
FC:1μg /test:
Species Reactivity HumanMouseRatCowHorseRabbit
Concentration 1mg/ml
Target Information
Alternative Names ARG3.1 Arc Arg 3.1 Activity regulated cytoskeletal associated protein Activity regulated cytoskeletal protein Activity-regulated cytoskeleton-associated protein Activity regulated cytoskeletal-associated protein ARC/ARG3.1 Activity-regulated gene 3.1 protein homolog Activity regulated gene 3.1 protein homolog Arg3.1 KIAA0278 ARC_HUMAN growth factor ARC.
Molecular Weight(MW) 45 KDa
Cellular Localization Cytoplasm, cytoskeleton. Endosome. Cytoplasmic vesicle, secretory vesicle, acrosome. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendrite. Cell projection, dendritic spine. Cell junction, synapse.
Database Links
SwissProt ID Q7LC44
Application

Application

Fig1: Sample: Brain (Rat) Lysate at 40 ug Brain (Mouse) Lysate at 40 ug Primary: Anti-ARC (ER1903-89) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kD Observed band size: 45 kD

Application

Fig2: Cell: A549 Concentration:1:100 Host/Isotype:Rabbit/IgG Flow cytometric analysis of primary antibody (Cat#: ER1903-89) on A549(green) compared with isotype control in the absence of primary antibody (blue) followed by Alexa Fluor 488-conjugated goat anti-rabbit IgG(H+L) secondary antibody .
Application Notes WB:1:500-2000:
FC:1μg /test:
Additional Information
Form Liquid
Storage Instructions Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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