Application
Fig1: Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-SLC10A2 (ER1903-97) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 38 kD Observed band size: 43 kD| Product Name | ASBT/SLC10A2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SLC10A2 Apical sodium dependent bile acid transporter Apical sodium- dependent bile acid transporter IBAT ileal apical sodium-dependent bile acid transporter Ileal sodium dependent bile acid transporter Ileal sodium-dependent bile acid transporter Ileal sodium/bile acid cotransporter ISBT Na+ bile acid cotransporter Na+ dependent ileal bile acid transporter NTCP2 Sodium/taurocholate cotransporting polypeptide, ileal solute carrier family 10 (sodium/bile acid cotransporter family) Solute carrier family 10 member 2. |
| Product description | This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism. |
| Immunogen | KLH conjugated synthetic peptide derived from human ASBT/SLC10A2 131-230/348 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRatDogCowHorseRabbit |
| Concentration | 1mg/ml |
| Alternative Names | SLC10A2
Apical sodium dependent bile acid transporter
Apical sodium- dependent bile acid transporter
IBAT
ileal apical sodium-dependent bile acid transporter
Ileal sodium dependent bile acid transporter
Ileal sodium-dependent bile acid transporter
Ileal sodium/bile acid cotransporter
ISBT
Na+ bile acid cotransporter
Na+ dependent ileal bile acid transporter
NTCP2
Sodium/taurocholate cotransporting polypeptide ileal solute carrier family 10 (sodium/bile acid cotransporter family) Solute carrier family 10 member 2. |
|---|---|
| Molecular Weight(MW) | 38 KDa |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| SwissProt ID | Q12908 |
|---|
Application
Fig1: Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-SLC10A2 (ER1903-97) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 38 kD Observed band size: 43 kD| Positive Control | Mouse Liver Lysate. |
|---|---|
| Application Notes | WB:1:500-2000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
