Application
Fig1: Western blot analysis of NOXA2 on rat spleen tissue lysate using anti-NOXA2 antibody at 1/500 dilution.Application
Fig2: Immunohistochemical analysis of paraffin-embedded rat spleen tissue using anti-NOXA2 antibody. Counter stained with hematoxylin.Application
Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-NOXA2 antibody. Counter stained with hematoxylin.Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-NOXA2 antibody. Counter stained with hematoxylin.| Product Name | NOXA2 [JG86-31] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 67 kDa neutrophil oxidase factor antibody Chronic granulomatous disease autosomal 2 antibody FLJ93058 antibody NADPH oxidase activator 2 antibody NCF-2 antibody Ncf2 antibody NCF2_HUMAN antibody Neutrophil cytosol factor 2 antibody Neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2) antibody Neutrophil NADPH oxidase factor 2 antibody NOXA2 antibody P67 PHOX antibody p67-phox antibody p67phox antibody |
| Product description | The heredity disease chronic granulomatous disease (CGF) has been linked to mutations in p47phox and p67phox. The cytosolic proteins p47phox and p67phox, also designated neutrophil cytosol factor 1(NCF1) and NCF2, respectively, are required for activation of the superoxide-producing NADPH oxidase in neutrophils and other phagocytic cells. During activation of the NADPH oxidase, p47phox and p67phox migrate to the plasma membrane where they associate with cytochrome b558 and the small G protein Rac to form the functional enzyme complex. Both p47phox and p67phox contain two Src homology 3 (SH3) domains. The C-terminal SH3 domain of p67phox has been shown to interact with the proline rich domain of p47phox, suggesting that p47phox may faciliate the transport of p67phox to the membrane. |
| Immunogen | Recombinant protein within Human NOXA2 aa 150-300. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCIP |
| WB:1:500 IHC:1:50-1:200 IP:1:10-1:50 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | 67 kDa neutrophil oxidase factor antibody
Chronic granulomatous disease autosomal 2 antibody
FLJ93058 antibody
NADPH oxidase activator 2 antibody
NCF-2 antibody
Ncf2 antibody
NCF2_HUMAN antibody
Neutrophil cytosol factor 2 antibody
Neutrophil cytosolic factor 2 (65kD chronic granulomatous disease autosomal 2) antibody Neutrophil NADPH oxidase factor 2 antibody NOXA2 antibody P67 PHOX antibody p67-phox antibody p67phox antibody |
|---|---|
| Molecular Weight(MW) | 60/47 kDa |
| Cellular Localization | Cytoplasm. |
Application
Fig1: Western blot analysis of NOXA2 on rat spleen tissue lysate using anti-NOXA2 antibody at 1/500 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded rat spleen tissue using anti-NOXA2 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-NOXA2 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-NOXA2 antibody. Counter stained with hematoxylin.| Positive Control | Rat spleen tissue, human spleen tissue, mouse spleen tissue. |
|---|---|
| Application Notes | WB:1:500 IHC:1:50-1:200 IP:1:10-1:50 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
