| Product Name | bFGF |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Basic fibroblast growth factor FGF basic FGF-basic BFGF FGF-2 FGF B FGF2 FGF2 basic FGFB Fibroblast growth factor 2 (basic) HBGF 2 HBGF-2 HBGF2 HBGH 2 HBGH2 Heparin binding growth factor 2 precursor Prostatropin FGF2_HUMAN. |
| Product description | FGF2, also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by the FGF2 gene It is synthesized primarily as a 155 amino acid polypeptide, resulting in an 18 kDa protein. However, there are four alternate start codons which provide N-terminal extensions of 41, 46, 55, or 133 amino acids, resulting in proteins of 22 kDa (196 aa total), 22.5 kDa (201 aa total), 24 kDa (210 aa total) and 34 kDa (288 aa total), respectively. Generally, the 155 aa/18 kDa low molecular weight (LMW) form is considered cytoplasmic and can be secreted from the cell, whereas the high molecular weight (HMW) forms are directed to the cell's nucleus. Like other FGF family members, basic fibroblast growth factor possess broad mitogenic and cell survival activities, and is involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. |
| Immunogen | KLH conjugated synthetic peptide derived from human bFGF 143-250/288 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC-PFC |
| WB:1:500-2000: IHC-P:1:400-800: FC:1μg/Test: |
|
| Species Reactivity | HumanMouseRatChickenCowRabbitSheep |
| Concentration | 1mg/ml |
| Alternative Names | Basic fibroblast growth factor
FGF basic
FGF-basic BFGF FGF-2 FGF B FGF2 FGF2 basic FGFB Fibroblast growth factor 2 (basic) HBGF 2 HBGF-2 HBGF2 HBGH 2 HBGH2 Heparin binding growth factor 2 precursor Prostatropin FGF2_HUMAN. |
|---|---|
| Molecular Weight(MW) | 18 KDa |
| Cellular Localization | Secreted. Nucleus. |
| SwissProt ID | P15655 |
|---|
| Positive Control | Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non-cancerous liver tissue. |
|---|---|
| Application Notes | WB:1:500-2000: IHC-P:1:400-800: FC:1μg/Test: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
