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BMP7

Catalog Number:OM629468
OM629468
Discount Price
OM629468-100ul
1~2 Week
100ul
OM629468-50ul
50ul
OM629468-20ul
20ul
1~2 Week
Product Profile
Product Name BMP7
Antibody Type Primary Antibodies
Antigen Alias bone morphogenetic protein 7 precursor osteogenic protein 1 BMP-7 OP-1 BMP 7 Bone morphogenic protein 7 Eptotermin alfa OP 1 OP1 BMP7_HUMAN.
Product description This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients.
Immunogen KLH conjugated synthetic peptide derived from human BMP7 293-350/431
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500-2000:
Species Reactivity HumanMouseRatChickenDogPigCowHorseRabbitSheep
Concentration 1mg/ml
Target Information
Alternative Names bone morphogenetic protein 7 precursor osteogenic protein 1 BMP-7 OP-1 BMP 7 Bone morphogenic protein 7 Eptotermin alfa OP 1 OP1 BMP7_HUMAN.
Molecular Weight(MW) 15.7/47 KDa
Cellular Localization Secreted.
Database Links
SwissProt ID P18075
Application

Application

Fig1: Sample: 293T Cell (Human) Lysate at 30 ug Primary: Anti-BMP7 (ER1904-26) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 15.7/47kD Observed band size: 49/40 kD

Application

Fig2: Sample: Bone (Mouse) Lysate at 40 ug Primary: Anti-BMP7 (ER1904-26) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 15.7/47 kD Observed band size: 47,50kD
Positive Control Expressed in the kidney and bladder. Lower levels seen in the brain.
Application Notes WB:1:500-2000:
Additional Information
Form Liquid
Storage Instructions Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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