Chromosome 6 open reading frame 25
G6b
G6B protein
Immunoglobulin receptor
MGC142279
MGC142281
NG31
Protein G6b
G6B_HUMAN.
Product description
Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. Appears to operate in a calcium-independent manner. Isoform B is a putative inhibitory receptor. Isoform A may be its activating counterpart.
Immunogen
KLH conjugated synthetic peptide derived from human C6orf25 1-100/241
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-2000:
Species Reactivity
HumanMouseRatCowSheep
Concentration
1mg/ml
Target Information
Alternative Names
Chromosome 6 open reading frame 25
G6b
G6B protein
Immunoglobulin receptor
MGC142279
MGC142281
NG31
Protein G6b
G6B_HUMAN.
Molecular Weight(MW)
24 KDa
Cellular Localization
Isoform E: Endoplasmic reticulum. Golgi apparatus.;Isoform D: Endoplasmic reticulum. Golgi apparatus.;Isoform B: Cell membrane; Single-pass type I membrane protein.;Isoform A: Cell membrane; Single-pass type I membrane protein.
Fig1: Protein: mouse testis lysate;
Primary: rabbit Anti-C6orf25 (ER1905-08) at 1:300;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000;
Predicted band size: 24 kD
Observed band size: 24 kD
Positive Control
Expressed in a restricted set of hematopoietic cell lines including the erythroleukemia cell line K-562 and the T-cell leukemia cell lines MOLT-4 and Jurkat. Not detected in the monocyte-like cell line U-937, the B-cell-like cell line Raji, the fibroblast cell lines TK and HeLa, or the natural killer cell lines NKL, NK 62 and YT. Expressed in platelets.
Application Notes
WB:1:500-2000:
Additional Information
Form
Liquid
Storage Instructions
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.