Application
Fig1: Sample: Small intestine (Mouse) Lysate at 40 ug Primary: Anti-CBR1 (ER1905-51) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 30 kD Observed band size: 30 kD| Product Name | CBR1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 15 hydroxyprostaglandin dehydrogenase [NADP+] 15-hydroxyprostaglandin dehydrogenase [NADP+] Carbonyl reductase [NADPH] 1 Carbonyl Reductase 1 CBR 1 CBR1 CBR1_HUMAN CRN NADPH dependent carbonyl reductase 1 NADPH-dependent carbonyl reductase 1 Prostaglandin 9 ketoreductase Prostaglandin 9-ketoreductase Prostaglandin E(2) 9 reductase Prostaglandin-E(2) 9-reductase SDR21C1. |
| Product description | NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione. |
| Immunogen | KLH conjugated synthetic peptide derived from human CBR1 201-277/277 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | 15 hydroxyprostaglandin dehydrogenase [NADP+] 15-hydroxyprostaglandin dehydrogenase [NADP+] Carbonyl reductase [NADPH] 1 Carbonyl Reductase 1 CBR 1 CBR1 CBR1_HUMAN CRN NADPH dependent carbonyl reductase 1 NADPH-dependent carbonyl reductase 1 Prostaglandin 9 ketoreductase Prostaglandin 9-ketoreductase Prostaglandin E(2) 9 reductase Prostaglandin-E(2) 9-reductase SDR21C1. |
|---|---|
| Molecular Weight(MW) | 30 KDa |
| Cellular Localization | Cytoplasm. |
| SwissProt ID | P16152 |
|---|
Application
Fig1: Sample: Small intestine (Mouse) Lysate at 40 ug Primary: Anti-CBR1 (ER1905-51) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 30 kD Observed band size: 30 kD| Application Notes | WB:1:500-2000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
