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KHSRP [JE41-64]

Catalog Number:OM629650
OM629650
Discount Price
OM629650-100ul
1~2 Week
100ul
OM629650-50ul
50ul
OM629650-20ul
20ul
1~2 Week
Product Profile
Product Name KHSRP [JE41-64]
Antibody Type Primary Antibodies
Antigen Alias Far upstream element-binding protein 2 antibody FBP2 antibody FUBP2 antibody FUBP2_HUMAN antibody FUSE binding protein 2 antibody FUSE-binding protein 2 antibody KH type splicing regulatory protein (FUSE binding protein 2) antibody KH type splicing regulatory protein antibody KH type-splicing regulatory protein antibody KHSRP antibody KSRP antibody p75 antibody
Product description Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Immunogen Recombinant protein within human KHSRP aa 1-150.
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Recombinant rabbit
Tested Applications WBICCIFIHCIP
WB:1:500-1:2,000
ICC/IF:1:50-1:200
IHC:1:50-1:200
IP:1:10-1:50
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Target Information
Alternative Names Far upstream element-binding protein 2 antibody FBP2 antibody FUBP2 antibody FUBP2_HUMAN antibody FUSE binding protein 2 antibody FUSE-binding protein 2 antibody KH type splicing regulatory protein (FUSE binding protein 2) antibody KH type splicing regulatory protein antibody KH type-splicing regulatory protein antibody KHSRP antibody KSRP antibody p75 antibody
Molecular Weight(MW) 73 kDa
Cellular Localization Nucleus. Cytoplasm.
Database Links
Application

Application

Fig1: Western blot analysis of KHSRP on different lysates using anti-KHSRP antibody at 1/1,000 dilution. Positive control: Lane 1: 293 Lane 2: mouse brain Lane 3: rat brain

Application

Fig2: ICC staining KHSRP in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig3: ICC staining KHSRP in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig4: ICC staining KHSRP in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig5: Immunohistochemical analysis of paraffin-embedded rat testis tissue using anti-KHSRP antibody. Counter stained with hematoxylin.

Application

Fig6: Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-KHSRP antibody. Counter stained with hematoxylin.

Application

Fig7: Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-KHSRP antibody. Counter stained with hematoxylin.

Application

Fig8: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-KHSRP antibody. Counter stained with hematoxylin.

Application

Fig9: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-KHSRP antibody. Counter stained with hematoxylin.
Positive Control 293, mouse brain tissue, rat brain tissue, 293T, LOVO, SH-SY-5Y, rat testis tissue, human lung cancer tissue, human colon tissue, human kidney tissue.
Application Notes WB:1:500-1:2,000
ICC/IF:1:50-1:200
IHC:1:50-1:200
IP:1:10-1:50
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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