CCDC100
CE120_HUMAN
Centrosomal protein of 120 kDa
Cep120
Coiled-coil domain-containing protein 100.
Product description
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis.
Immunogen
KLH conjugated synthetic peptide derived from human CEP120 351-450/986
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-2000:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
CCDC100
CE120_HUMAN
Centrosomal protein of 120 kDa
Cep120
Coiled-coil domain-containing protein 100.
Molecular Weight(MW)
112 KDa
Cellular Localization
Cytoplasm > cytoskeleton > centrosome. Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo.
Fig1: Sample: Lymph node (mouse) Lysate at 40 ug
Primary: Anti- CEP120(ER1906-14)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 112kD
Observed band size: 130kD
Application Notes
WB:1:500-2000:
Additional Information
Form
Liquid
Storage Instructions
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.