Application
Fig1: Sample:U251 Cell (Human) Lysate at 40 ug Primary: Anti-CHRM4(ER1906-24)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53kD Observed band size: 53kD| Product Name | CHRM4 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | mAChR M4 Muscarinic Acetylcholine Receptor M4 Cholinergic receptor muscarinic 4 Chrm 4 CHRM4 HM 4 HM4 M4 Muscarinic acetylcholine receptor M4 ACM4_HUMAN. |
| Product description | The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and postassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus. |
| Immunogen | KLH conjugated synthetic peptide derived from human CHRM4 131-230/479 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-2000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | mAChR M4 Muscarinic Acetylcholine Receptor M4 Cholinergic receptor muscarinic 4 Chrm 4 CHRM4 HM 4 HM4 M4 Muscarinic acetylcholine receptor M4 ACM4_HUMAN. |
|---|---|
| Molecular Weight(MW) | 53 KDa |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
| SwissProt ID | P08173 |
|---|
Application
Fig1: Sample:U251 Cell (Human) Lysate at 40 ug Primary: Anti-CHRM4(ER1906-24)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53kD Observed band size: 53kD| Application Notes | WB:1:500-2000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃. |
| Storage Buffer | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
